Effects of Unilateral WBV on Muscleactivity of Contralateral Hip Adductor (WBV-BM)

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Ilhan Karacan, Clinical Associated Professor, Bagcilar Training and Research Hospital
ClinicalTrials.gov Identifier:
NCT01419782
First received: August 17, 2011
Last updated: May 6, 2013
Last verified: May 2013

August 17, 2011
May 6, 2013
March 2011
November 2012   (final data collection date for primary outcome measure)
Vibration-induced contralateral muscle electrical activity [ Time Frame: 3 month ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01419782 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
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Effects of Unilateral WBV on Muscleactivity of Contralateral Hip Adductor
The Effects Of Femur On The Resting Myoelectrical Activity Of Contralateral Adductor Muscle During Unilateral Lower Extremity Vibration: Bone Myoregulation Reflex

The aim of this study is to investigate effects of femur exposed to unilateral vibration on the rest muscle electrical activity of contralateral hip adductors and contralateral soleus H-reflex in young adult men.

This study hypothesize that femur exposed to unilateral vibration may affect the rest muscle electrical activity of contralateral hip adductors. Vibration can effectively enhance muscle strength and power. Previous studies have shown that vibration increases muscle electromyographic (EMG) activity. It has been showed that bone has an effect on the increase in muscle EMG activity caused by vibration in healthy young adults in a study. In this study, it was reported that vibrations-induced increases in muscle electrical activity of flexor carpi radialis (FCR) was related to ultradistal radius bone mineral content (BMC) and the FCR H-reflex was suppressed or depressed during vibration. This findings were reported to support the assumption that the bone exposed to cyclic mechanical loading may neuronally regulate muscle activity.

A total of 20 voluntaries are planned to include in this study.

Vibration will be applied the right lower extremity by whole-body vibration (PowerPlate Pro). Cases will stand on vibration plate. WBV will be applied at a frequency of 40 Hz and amplitude of 2 mm for 60 seconds. WBV will be applied one session only.

The rest muscle electrical activity of ipsilateral and contralateral hip adductor muscles at rest will be measured by PowerLab (data acquisition system, ADInstruments, Australia) device.The rest-EMGrms will be measured at before and during vibration. We also evaluate a change in contralateral soleus H reflex during vibration.

Effects of bone on the rest muscle electrical activity will be assessed by hip bone mineral density, bone mineral content and serum sclerostin level. The right hip bone mineral density (BMD) and BMC will be evaluated by bone densitometer (Norland). Plasma sclerostin level will be measured by using Human Sclerostin ELISA kıt before and after vibration.

Interventional
Not Provided
Intervention Model: Single Group Assignment
Masking: Double Blind (Subject, Investigator)
Primary Purpose: Basic Science
  • Bone Mass
  • Effects of Vibration
Other: Whole-body vibration
Frequency: 40 Hz, vibration amplitude: 2 mm, duration: 60 sec
Other Name: Cyclic mechanical loading
Experimental: Whole-body vibration
whole body vibration will be applied the right lower limb.
Intervention: Other: Whole-body vibration
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
20
December 2012
November 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Age: 20-40 yrs
  • Gender: Male
  • Volunteer
  • Healthy status: Patients having hypoesthesia in his leg and Healthy subjects
  • Dominant hand:Right-handed

Exclusion Criteria:

  • Bone diseases (osteoporosis, osteomalacia, paget's disease, neoplasm, etc),
  • Systemic diseases (cardiovascular, endocrine, infections etc),
  • Myopathy-tendinopathy
  • Lower limb joint disease
  • Vertigo
  • Obesity (BMI >30 kg/m2)
  • Professional sportsman
  • Male doing regular sports activities
  • Skin disease in lower limb
  • Non-cooperative subject
  • Hemolysis of blood sample
Male
20 Years to 40 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Turkey
 
NCT01419782
BEAH FTR-5
No
Ilhan Karacan, Clinical Associated Professor, Bagcilar Training and Research Hospital
Bagcilar Training and Research Hospital
Not Provided
Principal Investigator: ILHAN KARACAN, MD Bagcilar Training & Research Hospital
Bagcilar Training and Research Hospital
May 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP