Attenuated Inflammatory Response in Laparoscopic Colon Surgery
This study has been completed.
Sponsor:
Oslo University Hospital
Information provided by (Responsible Party):
Dag T Førland, Oslo University Hospital
ClinicalTrials.gov Identifier:
NCT01419431
First received: July 18, 2011
Last updated: December 15, 2011
Last verified: December 2011
| Tracking Information | |||||
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| First Received Date ICMJE | July 18, 2011 | ||||
| Last Updated Date | December 15, 2011 | ||||
| Start Date ICMJE | January 2007 | ||||
| Primary Completion Date | November 2011 (final data collection date for primary outcome measure) | ||||
| Current Primary Outcome Measures ICMJE |
Inflammatory values for laparoscopic resection for colon cancer. [ Time Frame: 3 days ] [ Designated as safety issue: No ] Corresponding values of SOCS3 mRNA copared to inflammatory cytokines in patients with laparoscopic resection for colon cancer. |
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| Original Primary Outcome Measures ICMJE | Same as current | ||||
| Change History | Complete list of historical versions of study NCT01419431 on ClinicalTrials.gov Archive Site | ||||
| Current Secondary Outcome Measures ICMJE | Not Provided | ||||
| Original Secondary Outcome Measures ICMJE | Not Provided | ||||
| Current Other Outcome Measures ICMJE | Not Provided | ||||
| Original Other Outcome Measures ICMJE | Not Provided | ||||
| Descriptive Information | |||||
| Brief Title ICMJE | Attenuated Inflammatory Response in Laparoscopic Colon Surgery | ||||
| Official Title ICMJE | Increased SOCS 3 mRNA in Monocytes From Patients Subjected to Laparoscopic Colon Surgery | ||||
| Brief Summary | Pro-inflammatory responses following laparoscopic surgery. |
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| Detailed Description | Blood samples from 20 patient with colon cancer collected before and in 3 days following laparoscopic surgery. Analyzed for inflammatory cytokines and corresponding SOCS3 mRNA. |
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| Study Type ICMJE | Observational | ||||
| Study Design ICMJE | Observational Model: Cohort Time Perspective: Prospective |
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| Target Follow-Up Duration | Not Provided | ||||
| Biospecimen | Not Provided | ||||
| Sampling Method | Non-Probability Sample | ||||
| Study Population | Colon cancer stage I-III |
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| Condition ICMJE | Regulation of Inflammatory Response | ||||
| Intervention ICMJE | Procedure: Laparoscopic resection
Inflammatory response in laparoscopic surgery
Other Name: Colon cancer |
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| Study Group/Cohort (s) | Colon cancer patients
Laparoscopic resection
Intervention: Procedure: Laparoscopic resection |
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| Publications * | Not Provided | ||||
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* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline. |
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| Recruitment Information | |||||
| Recruitment Status ICMJE | Completed | ||||
| Estimated Enrollment ICMJE | 20 | ||||
| Completion Date | December 2011 | ||||
| Primary Completion Date | November 2011 (final data collection date for primary outcome measure) | ||||
| Eligibility Criteria ICMJE | Inclusion Criteria:Colon cancer stage I-III - Exclusion Criteria:Colon cancer stage IV - |
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| Gender | Both | ||||
| Ages | 18 Years and older | ||||
| Accepts Healthy Volunteers | No | ||||
| Contacts ICMJE | Contact information is only displayed when the study is recruiting subjects | ||||
| Location Countries ICMJE | Norway | ||||
| Administrative Information | |||||
| NCT Number ICMJE | NCT01419431 | ||||
| Other Study ID Numbers ICMJE | SOCS3 mRNA, SOCS-3-202008 | ||||
| Has Data Monitoring Committee | No | ||||
| Responsible Party | Dag T Førland, Oslo University Hospital | ||||
| Study Sponsor ICMJE | Oslo University Hospital | ||||
| Collaborators ICMJE | Not Provided | ||||
| Investigators ICMJE |
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| Information Provided By | Oslo University Hospital | ||||
| Verification Date | December 2011 | ||||
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ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP |
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