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Acceptability and Effectiveness of Household Water Treatment in Reducing Diarrhea Among Under Five Children

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Bezatu Mengiste, Haramaya Unversity
ClinicalTrials.gov Identifier:
NCT01376440
First received: June 16, 2011
Last updated: January 23, 2012
Last verified: January 2012

June 16, 2011
January 23, 2012
June 2011
October 2011   (final data collection date for primary outcome measure)
To assess the prevalence of diarrhea among under five children [ Time Frame: four months ] [ Designated as safety issue: Yes ]
weekly visit of the household for the presence of diarrhoea among underfive for four months in both the intervention and control groups
Same as current
Complete list of historical versions of study NCT01376440 on ClinicalTrials.gov Archive Site
  • To assess the weight gain among the intervention and control groups of under five children [ Time Frame: At the beginning and end of the study ( 4 months interval) ] [ Designated as safety issue: Yes ]
    This is designed to assess whether there is weight gain (objective outcome) in children assigned to the intervention group compared to the control group. It is supplement to the prevalence of diarrhea which is subjective outcome for this study
  • Residual chlorine test [ Time Frame: four months ] [ Designated as safety issue: Yes ]
    The use of the intervention (1.25% hypochlorite) is confirmed by the testing the residual chlorine weekly for for months from each household assigned in the intrevention group
To assess the weight gain among the intervention and control groups of under five children [ Time Frame: At the beginning and end of the study ( 4 months interval) ] [ Designated as safety issue: Yes ]
This is designed to assess whether there is weight gain (objective outcome) in children assigned to the intervention group compared to the control group. It is supplement to the prevalence of diarrhea which is subjective outcome for this study
Not Provided
Not Provided
 
Acceptability and Effectiveness of Household Water Treatment in Reducing Diarrhea Among Under Five Children
Acceptability and Effectiveness of Household Water Chlorination in Reducing the Prevalence of Diarrhea Among Under Five Children in Eastern Ethiopia

The Millenium development goals (MDGs) call for reducing by half the proportion of people without sustainable access to safe drinking water. This goal was adopted in large part because safe drinking water has been seen as critical to fighting diarrheal disease. Source protection is considered the main intervention area to achieve this goal. However, research worldwide that has shown that even drinking water which is safe at the source is subject to frequent and extensive fecal contamination during collection, storage and use in the home. This contamination is through the introduction of cups, dippers or hands, contamination by flies, cockroaches, and rats. Even piped water supplies of adequate microbial quality can pose infectious disease risks if they become contaminated due to unsanitary collection, storage conditions and practices within households.

To reduce this problem, point-of-use water treatment has been advocated as a means to substantially decrease the global burden of diarrhea and to contribute to the MDGs. However, research indicates that there are many unanswered questions around Household water treatment (HWT) that require small or medium scale epidemiological studies and randomized controlled trials, especially with regard to effectiveness, acceptability and identifying suitable target populations. Some of the most urgent questions to be resolved are:(1) How much of the currently cited disease reduction of HWT is due to bias? (2) What is the effect of HWT on nutritional status (weight gain and growth)?(3) At which populations should HWT be targeted? (4) Is it acceptable and sustainable in poor communities where the risk of diarrheal disease is high.

hypothesis: Do household water treatment with chlorine reduce diarrhea among underfive children? hypothesis: Do household water treatment with chlorine acceptable in the community?

Not Provided
Interventional
Phase 1
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
Acute Diarrhoea
Other: household water treatment
household water treatment with 1.25% sodium hypochlorite
Other Name: 1.25% sodium hypochlorite
  • Experimental: Household water treatment
    household water treatment with 1.25% sodium hypochlorite
    Intervention: Other: household water treatment
  • No Intervention: control
    Usual practice (the use of "Jerrican" for water storage, which is considered as safe storage)
Mengistie B, Berhane Y, Worku A. Household water chlorination reduces incidence of diarrhea among under-five children in rural Ethiopia: a cluster randomized controlled trial. PLoS One. 2013 Oct 23;8(10):e77887. doi: 10.1371/journal.pone.0077887.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
845
October 2011
October 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • All children under five years of age in the randomly selected clusters of Kersa district

Exclusion Criteria:

  • seriously sick children in the randomly selected clusters of Kersa district
Both
1 Month to 59 Months
No
Contact information is only displayed when the study is recruiting subjects
Ethiopia
 
NCT01376440
SGS13/15/11
Yes
Bezatu Mengiste, Haramaya Unversity
Haramaya Unversity
Not Provided
Principal Investigator: Bezatu M Alemu, M.Sc Assistant professor
Haramaya Unversity
January 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP