Application of Two Different Synthetic Sequential Media for the Human IVF-Embryo Transfer (IVF-ET) Program

This study has been completed.
Sponsor:
Information provided by:
Maria Fertility Hospital
ClinicalTrials.gov Identifier:
NCT01356238
First received: May 17, 2011
Last updated: May 18, 2011
Last verified: October 2009

May 17, 2011
May 18, 2011
November 2009
September 2010   (final data collection date for primary outcome measure)
Embryo Quality [ Time Frame: 3 Days ] [ Designated as safety issue: Yes ]
Same as current
Complete list of historical versions of study NCT01356238 on ClinicalTrials.gov Archive Site
Pregnancy and Implantation rates [ Time Frame: 2 months ] [ Designated as safety issue: Yes ]
Same as current
Not Provided
Not Provided
 
Application of Two Different Synthetic Sequential Media for the Human IVF-Embryo Transfer (IVF-ET) Program
Application of Two Different Synthetic Sequential Media for the Human IVF-ET Program

Quality-controlled commercial media have been used in many in-vitro fertilization (IVF) laboratories. However, commercial media are costly and difficult to compare directly because their exact compositions are not clearly indicated. Although commercially available media have commonly been used in most IVF programs worldwide, there are several advantages to the use of in-house synthetic sequential media at IVF laboratories. First, the results of quality control should be reliable due to a stringent protocol setting-up. Second, any direct supplementations or deletions of specific components are feasible to obtain good quality embryos and high pregnancy rates since those components can be defined. Finally, dependence on commercially available media diminishes so that the laboratory can more easily accommodate unexpected situations or problems, such as a sudden increase in IVF patients. Therefore, the present study was conducted to compare the efficacy of in-house MRC media in the human IVF-embryo transfer (ET) program to that of commercially available media.

Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Infertility
  • Other: MRC media
    Culture media
  • Other: Sydney IVF media
    Culture media
  • Experimental: MRC media
    Use MRC media in the human IVF-ET program
    Intervention: Other: MRC media
  • Active Comparator: Sydney IVF media
    Use Sydney IVF media in the human IVF-ET program
    Intervention: Other: Sydney IVF media
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
360
October 2010
September 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Patients undergoing IVF treatment in our clinic during study period

Exclusion Criteria:

  • Females older than 40 years
  • Patients showed fertilization failure
  • Patients with less than two 2PN embryos
Female
20 Years to 39 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Korea, Republic of
 
NCT01356238
MRC-1
Yes
Jeong Yoon, Maria Fertility Hospital
Maria Fertility Hospital
Not Provided
Principal Investigator: Jeong Yoon, M.S. Maria Fertility Hospital
Maria Fertility Hospital
October 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP