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Relationship Between Gestational Diabetes and Type 2 Diabetes (GDM)

This study is ongoing, but not recruiting participants.
Sponsor:
Information provided by (Responsible Party):
Julie Robitaille, Laval University
ClinicalTrials.gov Identifier:
NCT01340924
First received: March 15, 2011
Last updated: July 17, 2013
Last verified: July 2013

March 15, 2011
July 17, 2013
September 2009
September 2012   (final data collection date for primary outcome measure)
Glucose tolerance assessed using a 75g-Oral Glucose Tolerance Test (OGTT) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01340924 on ClinicalTrials.gov Archive Site
  • overweight/obesity [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • abdominal obesity [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • inflammatory state [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • metabolic syndrome [ Time Frame: 1 year ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Relationship Between Gestational Diabetes and Type 2 Diabetes
Key Determinants of Type 2 Diabetes Prevention Among Women With a History of Gestational Diabetes Mellitus

The overall objective of this research project is to study preventive practices among women with prior GDM and their impact on the T2D-related risk profile.

Type 2 diabetes (T2D) is a growing public health problem owing to its prevalence as well as its high morbidity and mortality rates. The identification of high-risk populations is of great importance particularly because the onset of T2D can be prevented or delayed by lifestyle modifications. Among high-risk populations, women with previously diagnosed gestational diabetes mellitus (GDM) are at particularly high risk of developing T2D. The success in reducing the occurrence of T2D among women with previous GDM could be achieved only if appropriate preventive measures are undertaken. According to the American Diabetes Association (ADA) and the Canadian Diabetes Association (CDA), lifestyle modifications aimed at reducing body weight and increasing physical activity are recommended and women are encouraged to be breastfeeding their infants. Certain factors have been suggested as determinants of behavioral practices in women with prior GDM including cognitive and environmental factors. A better understanding of these issues is essential for developing effective preventive strategies and possibly reducing the prevalence of T2D in the population.The overall objective of this research project is to study preventive practices among women with prior GDM and their impact on the T2D-related risk profile.

Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Retention:   Samples With DNA
Description:

whole blood; serum; white cell.

Non-Probability Sample

In order to avoid selection biases, we plan to recruit 450 women with a history of GDM through administrative data from the Régie de l'assurance maladie du Québec (RAMQ).

  • Gestational Diabetes
  • Type 2 Diabetes
Not Provided
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
450
December 2014
September 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Women aged ≥18 years with a diagnosis of GDM in the past 5 years based on the diagnosis data available from the RAMQ databanks.

Exclusion Criteria:

  • Pregnant women, women with type 1 diabetes.
Female
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Canada
 
NCT01340924
GDM
No
Julie Robitaille, Laval University
Laval University
Not Provided
Principal Investigator: Julie Robitaille, R.D., Ph.D. Laval University
Laval University
July 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP