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Ostoegenic Effects in Human Mesenchymal Stem Cells Enhanced by Wnt Signaling

The recruitment status of this study is unknown because the information has not been verified recently.
Verified March 2011 by China Medical University Hospital.
Recruitment status was  Not yet recruiting
Sponsor:
Information provided by:
China Medical University Hospital
ClinicalTrials.gov Identifier:
NCT01323894
First received: March 24, 2011
Last updated: March 25, 2011
Last verified: March 2011

March 24, 2011
March 25, 2011
March 2011
August 2012   (final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT01323894 on ClinicalTrials.gov Archive Site
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Ostoegenic Effects in Human Mesenchymal Stem Cells Enhanced by Wnt Signaling
Ostoegenic Effects in Human Mesenchymal Stem Cells Enhanced by Wnt Signaling/Hydroxyapatite Nanoparticles--Comparisons Between Non-viral and Viral Administration in Tissue Engineered Bone Regeneration

The first year purpose:

The best concentration of canonical Wnt3a will be investigated in promoting the osteoblastogenesis of human mesenchymal stem cells.

Our previous work is investigating the viral (Adv-BMP-2) administration for the development of a model to generate bones for possible use in clinical settings; the non-viral and viral administrations will be compared for best osteogenesis effects.

The first year purpose:

The best concentration of canonical Wnt3a will be investigated in promoting the osteoblastogenesis of human mesenchymal stem cells.

Observational
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Non-Probability Sample

The patients require surgery ner iliac or abdomen areas

Primary Disease
Not Provided
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Not yet recruiting
3
August 2013
August 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • age above 10 years old
  • The patients require surgery ner iliac or abdomen areas

Exclusion Criteria:

  • age below 10 years old
Both
10 Years to 80 Years
No
Taiwan
 
NCT01323894
DMR-99-IRB-122
Yes
Sophia Chia-Ning Chang, China Medical University Hospital
China Medical University Hospital
Not Provided
Principal Investigator: Sopha Chia-Ning Chang, M.D. Ph.D. China Medical University Hospital
China Medical University Hospital
March 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP