Physical Activity in Overweight Girls: Implications for Reversing Risk Factors for Type 2 Diabetes

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
University of Pittsburgh
ClinicalTrials.gov Identifier:
NCT01323088
First received: March 22, 2011
Last updated: April 12, 2013
Last verified: April 2013

March 22, 2011
April 12, 2013
August 2010
October 2012   (final data collection date for primary outcome measure)
Abdominal obesity, visceral fat [ Time Frame: 3 month ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01323088 on ClinicalTrials.gov Archive Site
insulin sensitivity by a 3-hour hyperinsulinemic-euglycemic clamp, oral glucose tolerance test, liver fat and intramyocellular lipid by 1H-magnetic resonance spectroscopy. [ Time Frame: 3 month ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Physical Activity in Overweight Girls: Implications for Reversing Risk Factors for Type 2 Diabetes
Physical Activity in Overweight Girls: Implications for Reversing Risk Factors for Type 2 Diabetes

In this randomized controlled trial, we will examine the effect of a 3-month exercise training (aerobic exercise versus resistance exercise) without calorie restriction on total and regional adiposity, ectopic fat in the liver and skeletal muscle, and risk of type 2 diabetes in overweight girls.

Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
  • Abdominal Obesity
  • Physical Activity
  • Other: Control
    Standard care control (no exercise)
  • Other: Resistance Exercise
    Supervised resistance exercise using stack weight equipments.
  • Other: Aerobic exercise
    Supervised aerobic exercise using treadmills, bikes, and ellipticals
  • Control
    Standard care control (no-exercise)
    Intervention: Other: Control
  • Active Comparator: Aerobic Exercise
    Intervention: Other: Aerobic exercise
  • Active Comparator: Resistance Exercise
    Intervention: Other: Resistance Exercise
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
44
October 2012
October 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Healthy overweight (BMI >-95th) youth between 12 and 18 years of age
  • Waist circumference >-75th percentile
  • Sedentary (no structured exercise >2 times/week for past 6 months)
  • Non-smokers, non-diabetic, no medical conditions
  • Weight stable for past 3 months

Exclusion Criteria:

  • Smokers
  • Diabetes
  • Psychiatric disorders
  • Syndromic obesity
  • Pregnancy
  • Taking medications known to affect study outcomes
Female
12 Years to 18 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01323088
1R21DK083654-01A1
Yes
University of Pittsburgh
University of Pittsburgh
Not Provided
Principal Investigator: SoJung Lee, PhD University of Pittsburgh
University of Pittsburgh
April 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP