Influence of Extracorporeal Circulation During Cardiac Surgery on the Development of Postoperative Thrombotic Thrombocytopenic Purpura (TTP)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified December 2011 by Johann Wolfgang Goethe University Hospitals.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Johann Wolfgang Goethe University Hospitals
ClinicalTrials.gov Identifier:
NCT01300117
First received: February 18, 2011
Last updated: December 28, 2011
Last verified: December 2011

February 18, 2011
December 28, 2011
October 2010
Not Provided
Change in ADAMTS13-Activity over time [ Time Frame: during surgery (at 1and 2 hours after beginning) and within the first 6 days after surgery ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01300117 on ClinicalTrials.gov Archive Site
  • Change in ADAMTS13-Antibody over time [ Time Frame: during surgery (at 1and 2 hours after beginning) and within the first 6 days after surgery ] [ Designated as safety issue: No ]
  • Change in Platelet count over time [ Time Frame: during surgery (at 1and 2 hours after beginning) and within the first 6 days after surgery ] [ Designated as safety issue: No ]
  • time duration of extracorporeal circulation during surgery [ Time Frame: during surgery ] [ Designated as safety issue: No ]
  • Amount of intraoperative given fluid replacement [ Time Frame: during surgery ] [ Designated as safety issue: No ]
  • Amount of given blood products (red blood cells) [ Time Frame: 24 hours ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Influence of Extracorporeal Circulation During Cardiac Surgery on the Development of Postoperative Thrombotic Thrombocytopenic Purpura (TTP)
Influence of Extracorporeal Circulation During Cardiac Surgery on the Development of Postoperative TTP

The purpose of this study is to determine whether extracorporeal circulation during cardiac surgery has an influence on ADAMTS13-Activity.

Not Provided
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Not Provided
Non-Probability Sample

Patients undergoing cardiac surgery at the University Hospital

Cardiac Surgery
Not Provided
  • with extracorporeal circulation
    Patients undergoing cardiac surgery with the use of an extracorporeal circulation
  • without extracorporeal circulation
    Patients undergoing cardiac surgery without the use of extracorporeal circulation (OPCAB)
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
70
Not Provided
Not Provided

Inclusion Criteria:

  • cardiac surgery with or without (OPCAB) the use of extracorporeal circulation
  • patient agrees

Exclusion Criteria:

  • no agreement
  • known TTP in medical history
Both
18 Years and older
No
Contact: Wolfgang Miesbach +49696301 ext 5051 wolfgang.miesbach@kgu.de
Contact: Imke R Reinecke ireineck@stud.uni-frankfurt.de
Germany
 
NCT01300117
TTP-KC
No
Dr. med. W. Miesbach, Hämophilie Zentrum, JWG University Hospital
Johann Wolfgang Goethe University Hospitals
Not Provided
Not Provided
Johann Wolfgang Goethe University Hospitals
December 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP