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Study of CPAP as Intervention After Lung Resection

This study has been completed.
Sponsor:
Information provided by:
University of Campinas, Brazil
ClinicalTrials.gov Identifier:
NCT01285648
First received: January 25, 2011
Last updated: January 26, 2011
Last verified: January 2011

January 25, 2011
January 26, 2011
November 2007
December 2009   (final data collection date for primary outcome measure)
Bubbling drains [ Time Frame: From immediate postoperative until fifth, along the study, in a total of one year ] [ Designated as safety issue: Yes ]
From the immediate postoperative day until hospital discharge, the presence of chest tubes and the occurrence of air leaks in them as evidenced by the bubbling of the water seal were recorded. The maintenance and removal of drains or their use with wall suction were determined by applying the medical protocol of the institution through the analysis of X-rays and the amount of drained fluid.
Same as current
Complete list of historical versions of study NCT01285648 on ClinicalTrials.gov Archive Site
Pain score [ Time Frame: Reported pain score after lung resection, along the study, during one year ] [ Designated as safety issue: Yes ]
Before beginning the chest physiotherapy protocols, the patient was asked to rate their pain from zero to ten according to its intensity (the larger the score, the greater the intensity of pain).
Same as current
Not Provided
Not Provided
 
Study of CPAP as Intervention After Lung Resection
APPLICATION OF CONTINUOUS POSITIVE AIRWAY PRESSURE IN POSTOPERATIVE OF LUNG RESECTION

The aim of this study was to compare the oxygenation index (OI), dyspnea, and pain scale and evaluate the duration of thoracic drainage and pleural air leaks after lung resection in two groups of patients: chest physiotherapy (CP) patients and combined CP and Continuous Positive Airway Pressure (CPAP) patients.

In pulmonary resection surgery complications that lead to significant functional losses of the lung parenchyma and alterations in the ventilatory function may trigger retention of secretions, atelectasis, pneumonia and respiratory failure, which prolong the duration of mechanical ventilation and hospitalisation and contribute to the increase in risk of mortality.

In this study the oxygenation index (OI), Borg Scale, pain scale and the presence and duration of thoracic drainage was determined in the immediate postoperative (POi) period and in the first and second postoperative (PO1, PO2) days in 40 patients who underwent elective lung resection.

Similar to Chest Physiotherapy, the preventive application of CPAP in the postoperative period after lung resection in our study also appeared to be a safe technique, which allowed improved oxygenation without increasing air leaks through the thoracic drains.

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Factorial Assignment
Masking: Open Label
Primary Purpose: Treatment
  • Lung Cancer
  • Pulmonary Complications
Procedure: Cpap
This study did not involved drugs. The Oxygenation index, Borg Scale, pain scale and the presence and duration of thoracic drainage was determined in the immediate postoperative (POi) period and in the first and second postoperative (PO1, PO2) days in 40 patients who underwent elective lung resection,in two groups of intervention: chest physiotherapy, and associate this with cpap
Other Names:
  • Noninvasive ventilation
  • lung resection
  • Cpap
    This group joined chest physiotherapy with CPAP via nasal masks for two hours.CPAP was continued from the immediate postoperative day until the second postoperative day, twice a day.
    Intervention: Procedure: Cpap
  • Chest Physiotherapy
    Chest Physiotherapy consisted of bronchial hygiene techniques and pulmonary expansion, in addition to exercises, and received oxygen supplementation to maintain the pulse oxymetry saturations > 90%.
    Intervention: Procedure: Cpap
Roceto Ldos S, Galhardo FD, Saad IA, Toro IF. Continuous positive airway pressure (CPAP) after lung resection: a randomized clinical trial. Sao Paulo Med J. 2014;132(1):41-7. doi: 10.1590/1516-3180.2014.1321525.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
40
February 2010
December 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • medical diagnosis of lung cancer and an indication for lung resection (lobectomy, bilobectomy and pneumonectomy) with posterolateral thoracotomy;
  • aged between 40 and 75 years.

Exclusion Criteria:

  • Patients who refused to participate in the survey;
  • lung resection with incisions other than posterolateral;
  • patients who had contraindications to the use of noninvasive ventilation.
Both
40 Years to 75 Years
No
Contact information is only displayed when the study is recruiting subjects
Brazil
 
NCT01285648
ROCETO130682
Yes
APPLICATION OF CONTINUOUS POSITIVE AIRWAY PRESSURE IN POSTOPERATIVE OF LUNG RESECTION, Unicamp
University of Campinas, Brazil
Not Provided
Principal Investigator: Lígia S. Roceto University of Campinas, Brazil
University of Campinas, Brazil
January 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP