Inflammatory Bowel Disease(IBD)Database

This study is not yet open for participant recruitment. (see Contacts and Locations)
Verified December 2010 by Tel-Aviv Sourasky Medical Center
Sponsor:
Information provided by:
Tel-Aviv Sourasky Medical Center
ClinicalTrials.gov Identifier:
NCT01266538
First received: December 23, 2010
Last updated: NA
Last verified: December 2010
History: No changes posted

December 23, 2010
December 23, 2010
January 2011
December 2026   (final data collection date for primary outcome measure)
flactuations in gastrointestinal inflammation [ Time Frame: ongoing, up to 4 times a year ] [ Designated as safety issue: No ]
Same as current
No Changes Posted
development of IBD-related morbidity and complications over time [ Time Frame: ongoing, up to 4 times a year ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Inflammatory Bowel Disease(IBD)Database
Epidemiologic, Clinical, Endoscopic and Histological Database of Patients With Inflammatory Bowel Disease (IBD)

This will be a comprehensive epidemiological, clinical, endoscopic and histological database for inflammatory bowel diseases patients in our medical center that will further provide clinical and basic investigations.

Inflammatory bowel diseases (IBD), which include Crohn's disease (CD), ulcerative colitis (UC), undefined IBD and pouchitis (in patients who required IPAA for their colitis) affects about two million people in the world. At this time there is no definitive cure and current treatment is aimed at managing the symptoms and inflammation that accompany these diseases. These diseases are predominantly chronic, and patients may experience various gastrointestinal symptoms depending on the location, nature, and extent of their disease. Both genetic and environmental factors play etiological roles. The overall goal of our research is to understand the etiology and course of these diseases in order to prevent and to manage cases more effectively. In order to do so we are aiming at building a comprehensive database that will include detailed clinical data conjoined with dedicated research information and collection of biological specimens that will target the gut epithelium immune system, the microbiota and specific genetic risk factors.

Observational
Time Perspective: Prospective
Not Provided
Retention:   Samples Without DNA
Description:

blood serum, gastrointestinal biopsies, fecal samples

Probability Sample
  1. Cases: Patients diagnosed with Inflammatory Bowel Disease (IBD) attending the departement of Gastroenterology (Tel Aviv Sourasky Medical Center) for a regular follow up / treatment.
  2. Controls:Family members of IBD patients, Patients with Irritable Bowel Syndrome (IBS), Fap (familial polyposis)patients after a large bowel resection, Patient performing screening endoscopy

    --------------------------------------------------------------------------------

Inflammatory Bowel Disease
Not Provided
  • IBD patients
    Patients diagnosed with Inflammatory Bowel Disease (IBD)
  • patients after a Large Bowel Resection
    Patients after a Large Bowel Resection, with or without a pouch.
  • Control group
    Family members of IBD patients, Patients with Irritable Bowel Syndrome (IBS), Fap (familial polyposis)patients after a large bowel resection, Patient performing screening endoscopy
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Not yet recruiting
2500
December 2026
December 2026   (final data collection date for primary outcome measure)

Inclusion Criteria:

Diagnosis of IBD Regular treatment and follow up in Tel Aviv Sourasky medical center Fap (familial polyposis)patients after a large bowel resection, as controls Family members of IBD patients as controls Patients with Irritable Bowel Syndrome (IBS), as controls -

Exclusion Criteria:

pregnancy age<18 years

-

Both
18 Years and older
Yes
Contact: Iris Dotan, MD PhD 972-3-6947305 irisd@tasmc.health.gov.il
Israel
 
NCT01266538
TASMC-10-ID-467-CTIL
No
Dr. Iris Dotan, Tel-Aviv Sourasky Medical Center
Tel-Aviv Sourasky Medical Center
Not Provided
Principal Investigator: Iris Dotan, MD PhD Tel-Aviv Sourasky Medical Center
Tel-Aviv Sourasky Medical Center
December 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP