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Computer-based Classification of Colorectal Polyps Using Narrow-band Imaging

This study has been completed.
Sponsor:
Information provided by:
Tischendorf, Jens, M.D.
ClinicalTrials.gov Identifier:
NCT01262248
First received: December 15, 2010
Last updated: June 15, 2011
Last verified: June 2011
History of Changes

December 15, 2010
June 15, 2011
May 2010
February 2011   (final data collection date for primary outcome measure)
diagnostic value (sensitivity, specificity, negative predictive value, positive predictive value, accuracy) [ Time Frame: 10 months ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01262248 on ClinicalTrials.gov Archive Site
interobserver variability [ Time Frame: 10 months ] [ Designated as safety issue: No ]
Same as current
Not Provided
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Computer-based Classification of Colorectal Polyps Using Narrow-band Imaging
Computer-based Classification of Small Colorectal Polyps

Recent studies have shown that narrow-band imaging (NBI) is a powerful diagnostic tool for the differentiation between neoplastic and non-neoplastic colorectal polyps. The aim of the present study is to develop and evaluate a computer-based method for automated classification of small colorectal polyps on the basis of vascularization features.In a prospective study 207 polyps with a size of 10mm or smaller should be detected by a zoom NBI colonoscopy. These polyps were imaged and subsequently removed for histological analysis. the polyp images were analyzed by a computer algorithm. The proposed computer-based method consists of several steps: preprocessing, vessel segmentation, feature extraction and classification. The results of the automatic classification (sensitivity, specificity, negative predictive value, positive predictive value and accuracy)were compared to those of human observers, who were blinded to the histological gold standard.
Not Provided
Observational
Observational Model: Cohort
Time Perspective: Prospective
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Probability Sample

patients who underwent colonoscopy and colorectal polyps with a size of 10mm or smaller were detected
Colorectal Polyps
Not Provided
patients with colorectal polyps

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
434
March 2011
February 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • All patients who did not meet the exclusion criteria were included in the study

Exclusion Criteria:

  • Patients with chronic inflammatory bowel disease, adenomatosis coli, coagulopathy, insufficient bowel preparation, or previous colonoscopy within the last 3 years; age under 18 years; no written informed consent for participation in the study
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Germany
 
NCT01262248
Ti-NBI
No
Tischendorf, Jens, M.D., Department of Medicine III, University of Aachen (RWTH)
Tischendorf, Jens, M.D.
Not Provided
Principal Investigator: Jens Tischendorf, M.D. Medical Department III, University Hospital Aachen (RWTH), Pauwelsstr. 30, 52074 Aachen
Tischendorf, Jens, M.D.
June 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP