Effect of Ambient Light on the Parameters of the Pupillary Light Reflex

This study has been completed.
Sponsor:
Information provided by:
Rutgers, The State University of New Jersey
ClinicalTrials.gov Identifier:
NCT01207817
First received: January 25, 2010
Last updated: September 22, 2010
Last verified: September 2010

January 25, 2010
September 22, 2010
September 2009
February 2010   (final data collection date for primary outcome measure)
pupillary light reflex: amplitude, latency, maximum constriction velocity, mean constriction velocity and dilation velocity during different levels of ambient light [ Time Frame: Pupillometry readings will be taken at 3 potential light readings low light, intermediate light and high ambient light. A total of 48 readings will be done. All parameters will be done at one sitting and will take approximately 45 minutes to complete. ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01207817 on ClinicalTrials.gov Archive Site
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Effect of Ambient Light on the Parameters of the Pupillary Light Reflex
Effect of Ambient Light on the Parameters of the Pupillary Light Reflex

The purpose of this study is to determine the effects of varying luminescent levels on the pupillary response.

Evaluation of the pupillary response is an underemphasized aspect of the assessment of visual function. The pupillary light reflex is one of the few objective indicators of afferent input from the retina and optic nerve. Since the pupillary light reflex is processed through the retina, it may be used to assess visual integrity (1). Pupillometry is a reliable technology capable of providing repetitive data on quantitative pupillary function in states of health and disease (2). Amplitude, latency, maximum constriction velocity, mean constriction velocity, and dilation velocity are measured using the Neuroleptics pupillometer. The effects of varying levels of ambient light on these parameters of the pupillary response have not been extensively studied. The purpose of this investigation is to determine the effects of varying luminescent levels on the pupillary response.

Observational
Observational Model: Case Control
Time Perspective: Prospective
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Non-Probability Sample

Healthy volinteers

Healthy Volunteers
Other: Pupillometry
Pupillometry readings will be taken at low, intermediate and high ambient light
no condition
no condition - healthy volunteers
Intervention: Other: Pupillometry
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
30
February 2010
February 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • healthy volunteers

Exclusion Criteria:

  • recent bout of conjunctivitis or infection in the eye recent eye surgery seizure disorder unable to lie flat for 30 minutes known history of eye disease which cannot be corrected with lenses
Both
18 Years to 65 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01207817
0120090181
No
Lawrence Chin, MD, UMDNJ
University of Medicine and Dentistry of New Jersey
Not Provided
Principal Investigator: Lawrence W Chinn, MD UMDNJ-NJMS
Rutgers, The State University of New Jersey
September 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP