Acupuncture for Migraine: a Functional Magnetic Resonance Imaging (fMRI) Study

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2012 by Chengdu University of Traditional Chinese Medicine.
Recruitment status was  Recruiting
Sponsor:
Information provided by (Responsible Party):
Chengdu University of Traditional Chinese Medicine
ClinicalTrials.gov Identifier:
NCT01152632
First received: June 27, 2010
Last updated: August 28, 2012
Last verified: August 2012

June 27, 2010
August 28, 2012
January 2010
June 2013   (final data collection date for primary outcome measure)
improvement of headache frequency [ Time Frame: 4 weeks ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01152632 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Acupuncture for Migraine: a Functional Magnetic Resonance Imaging (fMRI) Study
Acupuncture Treatment for Migraine: a Functional Magnetic Resonance Imaging Study

Selecting acupoints along meridians is the predominant principle in acupuncture treatment, and it is also considered to ensure acupuncture efficacy. This experiment is to investigate whether specific brain networks gradually come in formation in accordance with this kind of acupoint selection methods.

Every participants in the four intervention groups will go through functional magnetic imaging (fMRI) scan four times: the 1st scan will be performed at their baselines; the 2nd scan will be done after 2 courses (10 times) acupuncture treatment; the 3rd scan will be performed when the 4 courses end; the 4th scan will be operated after three-month enrollment.

Volunteers in waiting list group will undergo the above scans at the same time points in exception of acupuncture treatment.

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Outcomes Assessor)
Primary Purpose: Treatment
Migraine
Other: manual acupuncture
thirty minutes duration every time, five times per week for one course, a total four courses
Other Name: acupuncture
  • Experimental: specific points of Bladder meridian and Shanjiao meridian
    In traditional Chinese acupuncture theory, Bladder meridian and Shanjiao meridian have been considered as the main pathological meridian location of migraine. Meanwhile, specific points on both meridians have been used widely in its treatment for a long time.
    Intervention: Other: manual acupuncture
  • Experimental: non-specific points of Bladder meridian and Shanjiao meridian
    Non-specific points of Shaoyang meridians are also used in cure of migraine. It is conventionally thought to be less effective using non-specific points than specific ones.
    Intervention: Other: manual acupuncture
  • Active Comparator: specific points of Stomach meridian
    Specific points of Stomache meridian for migraine were searched in Chinese ancient data. And this group is set to compare with specific points of Shaoyang meridians for their possible different brain networks.
    Intervention: Other: manual acupuncture
  • Placebo Comparator: non-acupoints
    Three non-acupoints were chosen,two of which were located on the arm and one one the leg.
    Intervention: Other: manual acupuncture
  • No Intervention: waiting list
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
100
December 2013
June 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • clinical diagnosis of non-aura Migraine formulated by the international headache society in 2004

Exclusion Criteria:

  • people with other types of headache
  • people with organic cerebral disorders
  • people with primary disorders
  • people in moderate or severe anxiety or depression
  • people in pregnancy
Both
17 Years to 45 Years
No
Contact: Fanrong Liang, Master +86-13982253186 13982253186@139.com
China
 
NCT01152632
30930112/C190301
Yes
Chengdu University of Traditional Chinese Medicine
Chengdu University of Traditional Chinese Medicine
Not Provided
Study Chair: Fanrong Liang, Master Chengdu University of Traditional Chinese Medicine
Chengdu University of Traditional Chinese Medicine
August 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP