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Cheese and Human Health

The recruitment status of this study is unknown because the information has not been verified recently.
Verified October 2009 by University of Copenhagen.
Recruitment status was  Active, not recruiting
Sponsor:
Collaborators:
The Danish Dairy Research Foundation, Denmark
National Dairy Council
Information provided by:
University of Copenhagen
ClinicalTrials.gov Identifier:
NCT01140165
First received: June 4, 2010
Last updated: June 8, 2010
Last verified: October 2009
History of Changes

June 4, 2010
June 8, 2010
January 2010
June 2010   (final data collection date for primary outcome measure)
  • Total cholesterol [ Time Frame: 6 weeks ] [ Designated as safety issue: No ]
  • LDL cholesterol [ Time Frame: 6 weeks ] [ Designated as safety issue: No ]
  • HDL cholesterol [ Time Frame: 6 weeks ] [ Designated as safety issue: No ]
  • Triglyceride [ Time Frame: 6 weeks ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01140165 on ClinicalTrials.gov Archive Site
  • Insulin [ Time Frame: 6 weeks ] [ Designated as safety issue: No ]
  • Glucose [ Time Frame: 6 weeks ] [ Designated as safety issue: No ]
  • fasting hsCRP [ Time Frame: 6 weeks ] [ Designated as safety issue: No ]
  • Blood pressure [ Time Frame: 6 weeks ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Cheese and Human Health
Effects of Hard Cheese and Butter on Markers of Cardiovascular Disease -A Randomized Controlled Dietary Human Intervention

The aim of this study is to examine if a diet rich in cheese will have a beneficial effect on risk markers of cardiovascular disease compared to a diet rich in butter.

The primary parameters are total cholesterol as well as LDL-, HDL cholesterol and triacylglycerol (TAG). The secondary parameters are hsCRP, markers of insulin resistance, fasting insulin and glucose (HOMA). Furthermore bloodpressure is measured.
Not Provided
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Basic Science
Cardiovascular Disease
Other: cheese
the effect of cheese intake versus butter intake on blood lipids (primarily)
Other Name: cheese, butter, dairy
  • Active Comparator: butter
    Danish butter
    Intervention: Other: cheese
  • Experimental: cheese
    Intervention: Other: cheese
Hjerpsted J, Leedo E, Tholstrup T. Cheese intake in large amounts lowers LDL-cholesterol concentrations compared with butter intake of equal fat content. Am J Clin Nutr. 2011 Dec;94(6):1479-84. Epub 2011 Oct 26.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
60
December 2011
June 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Sign written consent
  • Age: 20-70
  • BMI: 20-32
  • Refrain from dietary supplements and blood donations prior to, and during the study

Exclusion Criteria:

  • Known or suspected abuse of alcohol, drugs or medication
  • Poor compliance
  • Current or previously cardiovascular disease
  • Diabetes Mellitus or other severe chronic disease, including severe allergies
Both
20 Years to 70 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Denmark
 
NCT01140165
A308
No
Tine Tholstrup, Dpt Human Nutrition, University of Copenhagen, Denmark
University of Copenhagen
  • The Danish Dairy Research Foundation, Denmark
  • National Dairy Council
Principal Investigator: Tine Tholstrup, PhD Department of Human Nutrition, University of Copenhagen
University of Copenhagen
October 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP