The Effect of DHEA on Markers of Ovarian Reserve in Women With Diminished Ovarian Reserve

This study has been terminated.
(Suboptimal recruitment)
Sponsor:
Information provided by (Responsible Party):
Fady I. Sharara, M.D, Virginia Center for Reproductive Medicine
ClinicalTrials.gov Identifier:
NCT01129830
First received: May 19, 2010
Last updated: September 18, 2014
Last verified: September 2014

May 19, 2010
September 18, 2014
January 2010
September 2014   (final data collection date for primary outcome measure)
live birth rate [ Time Frame: 3 years ] [ Designated as safety issue: No ]
Live birth rate will be monitored for women who took DHEA supplementation
Same as current
Complete list of historical versions of study NCT01129830 on ClinicalTrials.gov Archive Site
number of oocytes [ Time Frame: 3 years ] [ Designated as safety issue: No ]
Number of retrieved oocytes for patients undergoing IVF will be monitored along with ovarian response
Same as current
Not Provided
Not Provided
 
The Effect of DHEA on Markers of Ovarian Reserve in Women With Diminished Ovarian Reserve
The Effect of DHEA on Markers of Ovarian Reserve in Women With Diminished Ovarian Reserve

This prospective study evaluates the effect of DHEA supplementation on markers of ovarian reserve in women with diminished ovarian reserve.

Ovarian reserve markers, such as FSH, estradiol, AMH, ovarian volume and antral follicle counts will be monitored on DHEA supplementation in a prospective fashion.

Interventional
Phase 0
Allocation: Non-Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
Infertility
Dietary Supplement: dehydroepiandrosterone
DHEA supplementation 25 mg tid for 3 months
Dehydroepiandrosterone
infertile women with low anti mullerian hormone levels
Intervention: Dietary Supplement: dehydroepiandrosterone
Barad D, Brill H, Gleicher N. Update on the use of dehydroepiandrosterone supplementation among women with diminished ovarian function. J Assist Reprod Genet. 2007 Dec;24(12):629-34. Epub 2007 Dec 11.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Terminated
200
September 2014
September 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • infertile women with diminished ovarian reserve

Exclusion Criteria:

  • women > 45
Female
21 Years to 44 Years
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01129830
VCRM 3
Yes
Fady I. Sharara, M.D, Virginia Center for Reproductive Medicine
Virginia Center for Reproductive Medicine
Not Provided
Principal Investigator: Fady I Sharara, M.D Virginia Center for Reproductive Medicine
Virginia Center for Reproductive Medicine
September 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP