Magnetic Resonance Imaging (MRI) and Decline of Aging Aviator Performance

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2011 by Stanford University.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
Stanford University
ClinicalTrials.gov Identifier:
NCT01120860
First received: May 7, 2010
Last updated: June 9, 2011
Last verified: June 2011

May 7, 2010
June 9, 2011
November 2002
December 2012   (final data collection date for primary outcome measure)
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Not Provided
Complete list of historical versions of study NCT01120860 on ClinicalTrials.gov Archive Site
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Not Provided
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Magnetic Resonance Imaging (MRI) and Decline of Aging Aviator Performance
MRI and Decline of Aging Aviator Performance

The primary purpose of this study is to apply state-of-the-art Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopic Imaging (MRSI) techniques to measure changes over time in the brain.

We expect that MRI and MRSI techniques will be a useful adjunct in research efforts to understand individual differences in performance of a complex attention-demanding task, such as flying a plane or driving a car. Other predictors of change in performance of a complex task may include simple tests of processing speed and working memory, past training and recent practice of the task, and genetic risk factors for degenerative brain disease. In this project, we will examine whether baseline MR measures are as useful as longitudinal MR measures in predicting amount of change over time in task performance.

This research is part of a long-term effort to achieve earlier identification of individuals at risk of decline and ultimately minimize loss of function.

Observational
Observational Model: Cohort
Time Perspective: Prospective
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Non-Probability Sample

active healthy pilots

Memory
Device: MRI
MRI - routine imaging sequences, designed for anatomical quantification
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Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
100
December 2012
December 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Subjects will be included if they have participated in the protocol "Age-Related Longitudinal Changes in Aviator Performance" and agree to participate in this protocol.

Exclusion Criteria:

  • Subjects will be excluded if they currently have a major neurological disease, unstable/untreated medical disease (such as untreated hypertension).
  • In consideration of the magnetic fields in which subjects will be placed for the MR scanning, we will also exclude subjects who are unable to safely and comfortably complete the scanning session. This includes individuals who are wearing any metal prosthesis or who have cardiac pacemakers or any other nonremovable metal objects.
  • Subjects reporting a history of severe claustrophobia or poorly controlled back pain will be excluded because it is unlikely they could comfortably remain still in the MRI scanner for the duration of the scan.
  • In addition, subjects who do not fit in the apparatus will also be excluded.
Both
45 Years and older
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT01120860
SU-06302009-2941, 11097
No
Joy Taylor, Stanford University School of Medicine
Stanford University
Not Provided
Principal Investigator: Joy Taylor Stanford University
Stanford University
June 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP