Systematic Assessment of Competitive Flow in Coronary Artery Bypass Grafts by Wave Intensity Analysis

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2011 by Imperial College London.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Imperial College London
ClinicalTrials.gov Identifier:
NCT01118468
First received: May 5, 2010
Last updated: July 28, 2011
Last verified: July 2011

May 5, 2010
July 28, 2011
January 2010
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Complete list of historical versions of study NCT01118468 on ClinicalTrials.gov Archive Site
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Systematic Assessment of Competitive Flow in Coronary Artery Bypass Grafts by Wave Intensity Analysis
Systematic Assessment of Competitive Flow in Coronary Artery Bypass Grafts by Wave Intensity Analysis

Narrowing of the arteries that supply blood to the heart can lead to heart attacks and death. One way of treating this is to use artery and vein grafts from other parts of the body to bypass the narrowing. However, the blood flow from these grafts "competes" with flow through the natural coronary artery. This may contribute to grafts narrowing with time. This protocol aims to determine the pressure changes responsible for this effect. This could improve our understanding of why some grafts last longer than others.

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Observational
Time Perspective: Prospective
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Non-Probability Sample

Patients with previous bypass grafts undergoing angiography/ angioplasty who meet stduy criteria

Coronary Artery Bypass
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
40
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Inclusion Criteria:

  • Patients with previous coronary artery bypass grafts undergoing coronary angiography and graft restudy

Exclusion Criteria:

  • Patient's with cardiac pacemakers, valvular heart disease, and chronic renal failure
  • Unable to consent
  • Contraindications to adenosine
  • Contraindications to cardiac MRI
Both
18 Years and older
No
Contact: Justin E Davies, MRCP, PhD 020 7594 33 86 justin.davies@imperial.ac.uk
Contact: Sayan Sen, MRCP 020 7594 33 86 sayan.sen@imperial.ac.uk
United Kingdom
 
NCT01118468
1426
Yes
Dr Justin E Davies, Imperial College London
Imperial College London
Not Provided
Principal Investigator: Justin E Davies, MRCP PhD Imperial College London
Imperial College London
July 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP