Validation of the French Version of the Geriatric Mental State (GMS) (GMS-Package)

This study has been completed.
Sponsor:
Collaborator:
Institut National de la Santé Et de la Recherche Médicale, France
Information provided by (Responsible Party):
University Hospital, Tours
ClinicalTrials.gov Identifier:
NCT01061827
First received: February 2, 2010
Last updated: December 18, 2013
Last verified: August 2013

February 2, 2010
December 18, 2013
June 2008
June 2008   (final data collection date for primary outcome measure)
Diagnostic of dementia and depression [ Time Frame: four years ] [ Designated as safety issue: No ]
Validate the French version of the Geriatric Mental State package.The GMS is a standardised, semi-structured interview for examining and recording the mental state in elderly subjects. It allows the classification of patients by symptom profile and can demonstrate changes in profile over time.
Not Provided
Complete list of historical versions of study NCT01061827 on ClinicalTrials.gov Archive Site
Interjudge concordance for discrimination on control,depression and dementia patients [ Time Frame: 4 years ] [ Designated as safety issue: No ]
Measure the metrologic qualities, validition,sensibility, specificity against "gold standard" references as MADRS et CDR.
Not Provided
Not Provided
Not Provided
 
Validation of the French Version of the Geriatric Mental State (GMS)
Validation of the French Version of the Geriatric Mental State: a Structured and Standardized Interview for Diagnosis of Psychiatric Disorders in the Elderly

A major public health issues of today's aging population is the development of knowledge and expertise in geriatric medicine and psychiatry of the elderly. The depressive disorders and dementia, are among the psychiatric conditions most common in older age. They are the subject of much clinical research, in which brain imaging techniques used to establish correlations anatomo-clinical and radiological-clinical. The prerequisite for the realization of such work locally, is the validation in their French version of clinical assessment tools most commonly used internationally, ensuring reliability, acceptability and comparability of results. Among these tools, "Geriatric Mental Schedule (GMS) Package", is the reference tool for research in psychiatry of the elderly. It is a standardized and structured questionnaire that allows to establish with reliability and reproducibility on the basis of answers to questions, major psychiatric diagnoses in the elderly. It has been validated in several languages (German, Spanish, Italian, Dutch, but also Chinese, Korean ...), but is still not available in French.

Hypothesis: Validate the the French version of "Geriatric Mental Schedule (GMS) Package", to establish diagnoses of dementia and depressive disorders.

Patients 65 years or more, Nearest available to assist with the interview of informal caregivers For the subjects in the "dementia", meets the ICD-10 criteria for dementia, and CDR score at 1 to 2, with or without treatment For the subjects in the "depression", ICD-10 criteria for major depression, score on the depression scale MADRS of 18 or more, with or without treatment For control subjects, level of education based on the number of years of schooling (compulsory education until 16 years, extended school) Affiliation with a social security scheme Consent signed by the subject and the near Non-inclusion criteria Subjects with symptoms involving mixed dementia and depression such as not allowing complete ICD-10 criteria for dementia or depression.

Observational
Observational Model: Case-Only
Time Perspective: Prospective
Not Provided
Not Provided
Non-Probability Sample

Patients 65 years or more, Nearest available to assist with the interview of informal caregivers For the subjects in the "dementia", meets the ICD-10 criteria for dementia, and CDR score at 1 to 2, with or without treatment For the subjects in the "depression", ICD-10 criteria for major depression, score on the depression scale MADRS of 18 or more, with or without treatment For control subjects, level of education based on the number of years of schooling (compulsory education until 16 years, extended school)

Non-inclusion criteria Subjects with symptoms involving mixed dementia and depression such as not allowing complete ICD-10 criteria for dementia or depression.

Validate the French Version of "GMS Package" for the Diagnosis of Dementia and Depression.
Not Provided
  • Dementia
  • Depression
  • Control
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
96
November 2013
June 2008   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Nearest available to assist with the interview of informal caregivers For the subjects in the "dementia", meets the ICD-10 criteria for dementia, and CDR score at 1 to 2, with or without treatment For the subjects in the "depression", ICD-10 criteria for major depression, score on the depression scale MADRS of 18 or more, with or without treatment For control subjects, level of education based on the number of years of schooling (compulsory education until 16 years, extended school)

Exclusion Criteria:

  • Subjects with symptoms involving mixed dementia and depression such as not allowing complete ICD-10 criteria for dementia or depression.
Both
65 Years and older
No
Contact information is only displayed when the study is recruiting subjects
France
 
NCT01061827
AOHP/04/VC-GMS
Yes
University Hospital, Tours
University Hospital, Tours
Institut National de la Santé Et de la Recherche Médicale, France
Study Director: Vincent CAMUS, MD-PHD CHRU-Tours
Principal Investigator: Philippe NUBUKPO, MD-PHD CHU-Limoges
University Hospital, Tours
August 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP