The Effects of Joint Effusion on Proprioception

This study has been completed.
Sponsor:
Information provided by:
The Catholic University of Korea
ClinicalTrials.gov Identifier:
NCT01060215
First received: January 28, 2010
Last updated: February 1, 2010
Last verified: January 2010

January 28, 2010
February 1, 2010
May 2009
January 2010   (final data collection date for primary outcome measure)
Proprioceptive acuity in Knee Joint. Proprioceptive acuity (difference between the knee angles at the target and reproduced positions) was assessed by active repositioning of the lower limb after injection or no injection. [ Time Frame: within one hour after intervention ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT01060215 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
The Effects of Joint Effusion on Proprioception
Clinical Trial for the Effects of Joint Effusion on Proprioception

The purpose of this study is to assess the effects of joint effusion on proprioceptive status in patients with knee osteoarthritis (OA).

Proprioception is a sensory modality that provides feedback on the internal status of the body and enables us to perceive joint position and motion.

Osteoarthritis (OA), also called degenerative joint disease, is a major musculoskeletal condition characterized by loss of articular cartilage that leads to pain and loss of function. The most commonly affected joint is the knee, and OA may result in changes that affect not only intracapsular tissues, but also periarticular tissues, such as ligaments, capsules, tendons, and muscles. Many studies have examined the proprioceptive status of knee OA, and subjects with knee OA are known to have impaired proprioception compared with age-matched controls.

Joint effusion is a common symptom associated with chronic degenerative joint condition, but the effects of effusion on knee joint proprioception have not been investigated in detail.

A volume of 20 mL of normal saline was injected into the knee joint cavity of subjects in the experimental group under ultrasonographic guidance. Proprioceptive acuity was assessed by active repositioning of the lower limb using an electrogoniometer to measure knee joint position sense (JPS) under both non-weight-bearing and weight-bearing conditions twice, with a 20-min rest interval.

Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single Blind (Investigator)
Osteoarthritis
Procedure: Normal saline
20 cc normal saline injection into the knee joint
Other Name: Normal saline
  • Active Comparator: Infusion
    20cc saline infusion into the knee joint
    Intervention: Procedure: Normal saline
  • No Intervention: No infusion
    Intervention: Procedure: Normal saline
Cho YR, Hong BY, Lim SH, Kim HW, Ko YJ, Im SA, Lee JI. Effects of joint effusion on proprioception in patients with knee osteoarthritis: a single-blind, randomized controlled clinical trial. Osteoarthritis Cartilage. 2011 Jan;19(1):22-8. doi: 10.1016/j.joca.2010.10.013. Epub 2010 Oct 27.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
40
January 2010
January 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

Or at least two of criteria 2-6 established by the American College of Rheumatology (ACR):

  1. Kellgren and Lawrence (K/L) grade ≥II
  2. morning stiffness <30 min in duration
  3. crepitus on movement of the knee joint
  4. bony tenderness at the knee joint margins
  5. palpable or visible bony enlargement
  6. no palpable warmth.

Exclusion Criteria:

  1. the presence of knee joint effusion determined by ultrasonography
  2. a history of knee injury or surgery
  3. a history of knee injection within 3 months
  4. a history of inflammatory arthritis
  5. taking anticoagulants
  6. balance or gait disturbance
  7. diabetes mellitus.
Female
50 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Korea, Republic of
 
NCT01060215
52008B000100044
Yes
JongIn Lee/Department of Rehabilitation Medicine,, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea
The Catholic University of Korea
Not Provided
Study Chair: Jongin Lee, M.D Department of Rehabilitation Medicine, Seoul St. Mary's Hospital
The Catholic University of Korea
January 2010

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP