Cognitive Dysfunction After Aneurysmal Subarachnoid Haemorrhage

This study is currently recruiting participants. (see Contacts and Locations)
Verified April 2013 by Chinese University of Hong Kong
Sponsor:
Information provided by (Responsible Party):
George KC Wong, Chinese University of Hong Kong
ClinicalTrials.gov Identifier:
NCT01038193
First received: December 22, 2009
Last updated: April 22, 2013
Last verified: April 2013

December 22, 2009
April 22, 2013
March 2009
March 2014   (final data collection date for primary outcome measure)
Cognitive dysfunction [ Time Frame: 12 months ] [ Designated as safety issue: No ]
Cognitive dysfunction [ Time Frame: 9 months ] [ Designated as safety issue: No ]
Complete list of historical versions of study NCT01038193 on ClinicalTrials.gov Archive Site
  • Modified Rankin Scale [ Time Frame: 12 months ] [ Designated as safety issue: No ]
  • ShortForm36(SF-36) [ Time Frame: 12 months ] [ Designated as safety issue: No ]
  • Lawton-Instrumental-ActivityOfDailyLiving(IADL) [ Time Frame: 12 months ] [ Designated as safety issue: No ]
  • Stroke-specific-QOL [ Time Frame: 12 months ] [ Designated as safety issue: No ]
  • Modified Rankin Scale [ Time Frame: 9 months ] [ Designated as safety issue: No ]
  • SF-36 [ Time Frame: 9 months ] [ Designated as safety issue: No ]
  • Lawton-Instrumental-ADL [ Time Frame: 9 months ] [ Designated as safety issue: No ]
Not Provided
Not Provided
 
Cognitive Dysfunction After Aneurysmal Subarachnoid Haemorrhage
Cognitive Dysfunction After Aneurysmal Subarachnoid Haemorrhage

This is a longitudinal, multi-center, prospective study of aneurysmal subarachnoid haemorrhage patients in neurosurgical units in Hong Kong.

The investigators aim to recruit a total of 240 aneurysmal subarachnoid haemorrhage patients. The schedule for neuropsychological and functional assessments will be phased in at the second to third week, the third month, and the twelve months after the initial haemorrhage.

Observational
Observational Model: Case-Only
Time Perspective: Prospective
Not Provided
Not Provided
Non-Probability Sample

Aneurysmal subarachnoid hemorrhage patients

Cognitive Dysfunction
Other: Cognitive assessment
Cognitive and functional assessments at 2-4 weeks, 3 months and 12 months.
Other Name: Cognition
aSAH patients
Cognitive assessment
Intervention: Other: Cognitive assessment

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
240
March 2015
March 2014   (final data collection date for primary outcome measure)

Inclusion criteria

  1. Spontaneous subarachnoid haemorrhage with intracranial aneurysms as aetiology
  2. Admission within 96 hours of ictus
  3. Aged between 21 and 75 years
  4. A speaker of Chinese (Mandarin or Cantonese)
  5. Informed consent from patients or their legally acceptable representatives

Exclusion criteria

  1. History of previous cerebrovascular disease or neurological disease other than intracranial aneurysm
  2. History of neurosurgical operation prior to ictus
Both
21 Years to 75 Years
Yes
Contact: George KC Wong (852) 26321316
Contact: Shirley Chiu (852) 26322624
China
 
NCT01038193
GW004
Yes
George KC Wong, Chinese University of Hong Kong
Chinese University of Hong Kong
Not Provided
Principal Investigator: George KC Wong Division of Neurosurgery, CUHK
Chinese University of Hong Kong
April 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP