Role of Oral Glutathione in Skin Whitening

This study has been completed.
Sponsor:
Information provided by:
Chulalongkorn University
ClinicalTrials.gov Identifier:
NCT01016080
First received: November 17, 2009
Last updated: NA
Last verified: November 2009
History: No changes posted

November 17, 2009
November 17, 2009
February 2009
May 2009   (final data collection date for primary outcome measure)
Skin melanin index [ Time Frame: 4 weeks ] [ Designated as safety issue: Yes ]
Same as current
No Changes Posted
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Role of Oral Glutathione in Skin Whitening
Glutathione as an Oral Whitening Agent: a Randomized, Double-blind, Placebo-controlled Study

Oral and intravenous glutathione have been used widely to whiten the skin. The investigators tested this hypothesis by giving oral glutathione for 4 weeks to medical students.

Not Provided
Interventional
Phase 1
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
Skin Whitening
  • Drug: glutathione
    250 mg capsules, twice daily, orally
  • Drug: placebo
    250 mg capsules, twice daily, orally
  • Active Comparator: oral glutathione
    glutathione, 500 mg, taken orally twice daily
    Intervention: Drug: glutathione
  • Placebo Comparator: placebo capsules
    identical-appearing placebo capsules
    Intervention: Drug: placebo
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
60
June 2009
May 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Healthy medical students

Exclusion Criteria:

  • history of skin cancer, especially melanoma
  • consumption of any preparations containing glutathione within 1 month of enrollment
  • pigmentary disorders or any dermatoses
Both
18 Years to 25 Years
Not Provided
Contact information is only displayed when the study is recruiting subjects
Thailand
 
NCT01016080
COA840/2008
No
Pravit Asawanonda, Chulalongkorn University
Chulalongkorn University
Not Provided
Not Provided
Chulalongkorn University
November 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP