Aerobic Exercise to Improve Executive Language Function In Older Adults

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Department of Veterans Affairs
ClinicalTrials.gov Identifier:
NCT00979069
First received: September 15, 2009
Last updated: June 30, 2014
Last verified: June 2014

September 15, 2009
June 30, 2014
September 2010
January 2012   (final data collection date for primary outcome measure)
Executive Language Functions [ Time Frame: pre and post separated by 12 weeks ] [ Designated as safety issue: No ]
Executive Language Functions [ Time Frame: pre and post seperated by 12 weeks ] [ Designated as safety issue: No ]
Complete list of historical versions of study NCT00979069 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Aerobic Exercise to Improve Executive Language Function In Older Adults
Aerobic Exercise to Improve Executive Language Function in Older Adults

The purpose of this study is to see if exercise can improve brain function in older adults

Recently, considerable attention has been devoted to examining the beneficial relationship between cognition and aerobic exercise in older adults. Specifically, the effects are thought to involve higher order cognitive processes, such as working memory, switching between tasks, and inhibiting irrelevant information, all of which are thought to be sub- served, in part, by the frontal lobes (Colcombe et al., 2006). Importantly, these areas also are most susceptible to age-related decline (Raz, 2000) and are essential resources for language production (Kemper & Sumner, 2001; Murray & Lenz, 2001). However, despite promising cognitive improvement, changes in frontally-mediated executive language functions have been widely ignored. This is unfortunate considering impaired word retrieval compromises communicative effectiveness, leading to frustration, depression, and withdrawal. Perhaps more importantly, communication ineffectiveness, particularly in the elderly, leads to difficulties interacting with health care professionals leading to further health care burdens. Since cognition, and specifically word retrieval difficulties, usually remain untreated, it is important to find treatment strategies for minimizing these deficits. Therefore, the short-term goal and the purpose of this proposal is to examine the potential of aerobic exercise to improve executive language function in older adults.

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Aging
  • Behavioral: Aerobic group
    12 weeks of aerobic exercise 3 times a week
  • Behavioral: Strength training
    12 weeks of strength training 3 times a week
  • Experimental: Arm 1
    12 weeks of aerobic exercise 3 times a week
    Intervention: Behavioral: Aerobic group
  • Active Comparator: Arm 2
    12 weeks of strength training 3 times a week
    Intervention: Behavioral: Strength training
Nocera J, McGregor KM, Hass C, Crosson B. 'Spin' Exercise Improves Semantic Fluency in Previously Sedentary Older Adults. J Aging Phys Act. 2014 Jan 14. [Epub ahead of print]

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
50
January 2012
January 2012   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Consent of participants' primary health care physicians to participate in the aerobic exercise.
  • Patients must not have participated in any consistent exercise program or experimental study for at least 3 months prior to enrollment.
  • They must be capable of providing informed consent and complying with the trial procedures.

Exclusion Criteria:

  • Demented as defined by the Modified Mini Mental Status Exam.
  • Unalterable travel schedules.
  • Site accessibility constraints.
Both
55 Years to 75 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00979069
E6860-M
No
Department of Veterans Affairs
Department of Veterans Affairs
Not Provided
Principal Investigator: Joe R Nocera, PhD Atlanta VA Medical and Rehab Center, Decatur, GA
Department of Veterans Affairs
June 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP