Prevention of Intradialytic Hypotension in Acute Kidney Injury Patients

This study has been completed.
Sponsor:
Collaborator:
Fundação de Amparo à Pesquisa do Estado de São Paulo
Information provided by:
Sao Jose do Rio Preto University
ClinicalTrials.gov Identifier:
NCT00971971
First received: September 3, 2009
Last updated: September 4, 2009
Last verified: September 2009

September 3, 2009
September 4, 2009
October 2005
July 2007   (final data collection date for primary outcome measure)
Intradialytic hypotension [ Time Frame: At dialysis session ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00971971 on ClinicalTrials.gov Archive Site
Dialysis dose [ Time Frame: dialysis session ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Prevention of Intradialytic Hypotension in Acute Kidney Injury Patients
Assessment of a Protocol Aiming to Prevent Intradialytic Hypotension in Critically Ill Acute Kidney Injury Patients

Intradialytic hypotension (IH) is a major complication during acute hemodialysis. The aim of this study was to evaluate the effects of dialysate temperature (DT) reduction with Na and ultrafiltration (UF) profiling on hemodynamics of critically ill acute kidney injury (AKI) patients submitted to sustained low-efficiency dialysis (SLED).

Not Provided
Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
  • Acute Kidney Injury
  • Acute Renal Failure
  • Procedure: Dialysis
    dialysate temperature (DT) reduction with Na and ultrafiltration (UF) profiling
  • Procedure: Standard SLED
  • No Intervention: Control
    Traditional SLED
    Intervention: Procedure: Standard SLED
  • Experimental: Profiling
    dialysate temperature reduction with Na and ultrafiltration (UF) profiling
    Intervention: Procedure: Dialysis
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
40
September 2009
July 2007   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Acute renal failure with a need of dialysis.

Exclusion Criteria:

  • Patients with basal serum creatinine > 3 mgdL.
  • Patients submitted to renal transplantation.
  • Patients unlikely to survive.
  • Declination in authorization to participation in the study.
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
Brazil
 
NCT00971971
10727-6
No
Emerson Quintino de Lima MD, PhD, Associate Professor, Nephrology Division, São JOsé do Rio Preto Medical School
Sao Jose do Rio Preto University
Fundação de Amparo à Pesquisa do Estado de São Paulo
Not Provided
Sao Jose do Rio Preto University
September 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP