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Correlation of Particulate Matter and Heme Oxygenase-1 Protein Activity in Asthmatic Children by Induced Sputum Analysis.

The recruitment status of this study is unknown because the information has not been verified recently.
Verified November 2009 by Tel-Aviv Sourasky Medical Center.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Tel-Aviv Sourasky Medical Center
ClinicalTrials.gov Identifier:
NCT00969670
First received: August 29, 2009
Last updated: November 21, 2009
Last verified: November 2009

August 29, 2009
November 21, 2009
October 2009
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Complete list of historical versions of study NCT00969670 on ClinicalTrials.gov Archive Site
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Correlation of Particulate Matter and Heme Oxygenase-1 Protein Activity in Asthmatic Children by Induced Sputum Analysis.
Correlation of Particulate Matter and Heme Oxygenase-1 Protein Activity in Asthmatic Children by Induced Sputum Analysis.

Samples of sputum from asthmatic children, between 5-17 years, will be collected during two years of the study period to perform tests Particle Size Distribution (PSD) and Shape Analysis (SA) of the particulate matter in the sputum and a biochemical reaction to evaluate the activity of Heme Oxygenase-1 protein in sputum cell supernatants.

Each child will perform Pulmonary Function Testing (PFT) and Induced Sputum (IS) as a routine part of diagnosis of asthma.

Parents will be asked to complete a questionnaire including questions on their child's respiratory symptoms in the last 12 months as well as socioeconomic factors. Parents will be asked to give informed written consent for their child's participation in the study.

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Observational
Observational Model: Ecologic or Community
Time Perspective: Cross-Sectional
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Retention:   Samples Without DNA
Description:

Samples of indused sputum

Non-Probability Sample

Children, between 5-17 years, performing a routine diagnosis of asthma in Tel Aviv Sourasky Medical Center

Asthma
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
100
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Inclusion Criteria:

  • •All children, between 5-17 years, performing a routine diagnosis of asthma in Tel Aviv Sourasky Medical Center that there parents gave informed written consent for their child's participation in the study.

Exclusion Criteria:

  • None.
Both
5 Years to 17 Years
Yes
Israel
 
NCT00969670
TASMC-09-LF-242-CTIL
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Elizabeth Fierman, PhD, Tel-Aviv Sourasky Medical Center
Tel-Aviv Sourasky Medical Center
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Tel-Aviv Sourasky Medical Center
November 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP