Evaluation of the Quality of Cardio-Pulmonary Resuscitation (CPR) in Cardiac Arrest Patients

This study is currently recruiting participants. (see Contacts and Locations)
Verified April 2013 by Tampere University Hospital
Sponsor:
Collaborators:
Turku University Hospital
Uppsala University
Information provided by (Responsible Party):
Arvi Yli-Hankala, Tampere University Hospital
ClinicalTrials.gov Identifier:
NCT00951704
First received: July 31, 2009
Last updated: April 15, 2013
Last verified: April 2013

July 31, 2009
April 15, 2013
November 2008
December 2015   (final data collection date for primary outcome measure)
  • The success rate of current guidelines (depth and frequency of chest compression, epidemiology) [ Time Frame: During the resuscitation ] [ Designated as safety issue: No ]
  • Quality of life after CA [ Time Frame: 6 months ] [ Designated as safety issue: No ]
    Quality of life after CA is usually fairly good measurement of quality of resuscitation attempt
The success rate of current guidelines (depth and frequency of chest compression) [ Time Frame: During the resuscitation ] [ Designated as safety issue: No ]
Complete list of historical versions of study NCT00951704 on ClinicalTrials.gov Archive Site
  • Invasive arterial pressures, cerebral oxygenation (NIRS), EtCO2 [ Time Frame: During the resuscitation ] [ Designated as safety issue: No ]
  • survival of cardiac arrest [ Time Frame: hospital discharge ] [ Designated as safety issue: No ]
Invasive arterial pressures, cerebral oxygenation (NIRS) [ Time Frame: During the resuscitation ] [ Designated as safety issue: No ]
Change in hemodynamics, Change in cerebral saturation, Change in quality of CPR [ Time Frame: During resuscitation ] [ Designated as safety issue: Yes ]
Not Provided
 
Evaluation of the Quality of Cardio-Pulmonary Resuscitation (CPR) in Cardiac Arrest Patients
Evaluating the Quality of Prehospital and In-hospital Cardio-pulmonary Resuscitation by Reviewing Defibrillator Records - Comparing the Compressions to Concurrent Vital Signs (Invasive Blood Pressure, Cerebral Oxygen Saturation, EtCO2) and Iatrogenic Injuries Associated to Chest Compressions.

The prognosis of cardiac arrest patients is generally poor. Recent studies have showed that the high quality of CPR increases the survival after cardiac arrest. Therefore the investigators planned this prospective observational study to determine the epidemiology of sudden cardiac arrest in the prehospital setting of Tampere area, the quality of the CPR, and also the associations between depth and frequency of chest compressions and invasive arterial pressure, EtCO2,cerebral oxygenation and iatrogenic injuries associated to chest compressions 1) in patients resuscitated out of hospital by emergency medical service's (EMS's) personals and 2) in-hospital by hospital resuscitation team members. In addition, the investigators will analyze the effects of the chosen method of resuscitation on critical vital signs (Etco2 and invasive pressures): closed-chest CPR is compared to open-chest CPR, or mechanical CPR with a device (AutoPulse-CPR, Cardio Pump) compared to manual CPR guided with quality CPR device. The results will give the investigators important insights into the haemodynamics of CPR which may guide future strategies for the management of cardiac arrest. The research group is also interested in CPR related injuries and mattress effect. Quality of life after CA is evaluated among survivals and the cause of death among non-survivors.

Not Provided
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Not Provided
Probability Sample

Adult population >18 years of age with cardiac arrest

Cardiac Arrest
Not Provided
Cardiac arrest

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
500
December 2017
December 2015   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • cardiac arrest
  • > 18 years of age

Exclusion Criteria:

  • < 18 years of age
Both
18 Years and older
No
Contact: Sanna Hoppu, MD, PhD +358503624711 sanna.hoppu@fimnet.fi
Contact: Marko Sainio, MD +358505342399 marko.sainio@fimnet.fi
Finland
 
NCT00951704
R08116
Yes
Arvi Yli-Hankala, Tampere University Hospital
Tampere University Hospital
  • Turku University Hospital
  • Uppsala University
Study Director: Jyrki Tenhunen, MD, PhD Critical Care Medicine Research Group
Principal Investigator: Sanna Hoppu, MD, PhD Critical Care Medicine Research Group
Principal Investigator: Marko Sainio, MD Critical Care Medicine Research Group
Study Director: Klaus Olkkola, MD, PhD Turku University Hospital
Principal Investigator: Heidi Hellevuo, MB Critical Care Medicine Research Group
Principal Investigator: Piritta Setälä, MD Tampere University Hospital
Study Director: Ilkka Virkkunen, MD, PhD Tampere University Hospital
Tampere University Hospital
April 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP