Prokinetic Drugs and Enteral Nutrition (prokinetics)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified June 2009 by Universitair Ziekenhuis Brussel.
Recruitment status was  Not yet recruiting
Sponsor:
Information provided by:
Universitair Ziekenhuis Brussel
ClinicalTrials.gov Identifier:
NCT00916591
First received: June 5, 2009
Last updated: NA
Last verified: June 2009
History: No changes posted

June 5, 2009
June 5, 2009
September 2009
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No Changes Posted
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Prokinetic Drugs and Enteral Nutrition
Effect of Prokinetic Drugs During the Administration of Enteral Nutrition

The purpose of this study is to compare the effect of two drugs that can help in the prevention of regurgitation during the administration of enteral nutrition and define which one is the most effective.

Two prokinetic drugs (metoclopramide and erythromycin) will be compared during the administration of enteral nutrition in critically ill patients. We would like to know which one is the most effective in preventing regurgitation and risk of aspiration, which is a common complication of enteral nutritional support. This will be evaluated by measuring gastric residue every six hours.

Observational
Observational Model: Cohort
Time Perspective: Prospective
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Non-Probability Sample

Critically ill patients, intubated and mechanically ventilated, 18 years or older

  • Critically Ill
  • Enteral Nutrition
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Not yet recruiting
60
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Inclusion Criteria:

  • critically ill patients
  • intubated
  • mechanically ventilated
  • 18 or older age
  • enterally fed

Exclusion Criteria:

  • prokinetic drugs before start study
  • allergy to study medication
  • interactions odf study medication with other drugs
  • recent gastro-intestinal surgery
  • history of esophagectomy or gastrectomy
  • suspicion of gastrointestinal perforation
  • myasthenia gravis
  • liver dysfunction
  • less than 7 days in study
  • gastro- or jejunostomy
Both
18 Years and older
No
Contact: Nele Van De Winkel 00324773348 nelevandewinkel@hotmail.com
Belgium
 
NCT00916591
UZBrussels, 2009-012342-23
Yes
Van De Winkel Nele MD, UZBrussels
Universitair Ziekenhuis Brussel
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Universitair Ziekenhuis Brussel
June 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP