The Use of Narrow Band Imaging in Screening Colonoscopy

This study has been completed.
Sponsor:
Information provided by:
Valduce Hospital
ClinicalTrials.gov Identifier:
NCT00908648
First received: January 22, 2009
Last updated: April 2, 2009
Last verified: April 2009

January 22, 2009
April 2, 2009
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Adenoma Detection [ Time Frame: duration of colonoscopy procedure ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00908648 on ClinicalTrials.gov Archive Site
Detection of Flat and/or Depressed Adenomas [ Time Frame: duration of colonoscopy procedure ] [ Designated as safety issue: No ]
Same as current
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The Use of Narrow Band Imaging in Screening Colonoscopy
The Impact of Narrow Band Imaging in Screening Colonoscopy: a Randomized Controlled Trial.

Narrow band imaging (NBI) is an imaging technique that allows a better definition of capillary pattern and improves the contrast between adenomas and the surrounding mucosa. Conflicting data exist on the ability of NBI in to improve detection of colonic neoplasm; the impact of NBI is being tested in several screening scenarios. The investigators evaluated whether the routine use of NBI, compared to white light (WL), during the withdrawal phase of screening colonoscopy improved adenoma detection.

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Interventional
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Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind
Primary Purpose: Diagnostic
Colonoscopy
Procedure: Narrow Band Imaging
Narrow Band Imaging
  • No Intervention: 1
    standard white light
  • Experimental: 2
    Narrow Band Imaging
    Intervention: Procedure: Narrow Band Imaging

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
206
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Inclusion Criteria:

  • 50-69 year-old asymptomatic subjects at average-risk of CRC
  • positive FOBT participating in a national mass-screening program and referred for colonoscopy

Exclusion Criteria:

  • ongoing anticoagulation therapy
  • inadequate bowel cleansing
  • incomplete colonoscopy
  • refusing to participate
Both
50 Years to 69 Years
No
Contact information is only displayed when the study is recruiting subjects
Not Provided
 
NCT00908648
NBI-01
No
Vittorio Terruzzi, MD., Valduce Hospital, Department of Gastroenterology
Valduce Hospital
Not Provided
Not Provided
Valduce Hospital
April 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP