Trial record 1 of 1 for:    AOST06B1
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Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma

This study is currently recruiting participants. (see Contacts and Locations)
Verified November 2012 by National Cancer Institute (NCI)
Sponsor:
Collaborator:
Information provided by:
National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:
NCT00899275
First received: May 9, 2009
Last updated: November 22, 2012
Last verified: November 2012

May 9, 2009
November 22, 2012
February 2008
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  • Collect biological specimens from patients with osteosarcoma [ Designated as safety issue: No ]
  • Provide a repository for long-term storage of osteosarcoma-related biological materials [ Designated as safety issue: No ]
  • Make these specimens available to qualified researchers to understand the biology of osteosarcoma [ Designated as safety issue: No ]
  • Correlate these results with the patients' clinical data [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00899275 on ClinicalTrials.gov Archive Site
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Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma
A Children's Oncology Group Protocol for Collecting and Banking Osteosarcoma Specimens

RATIONALE: Collecting and storing samples of tumor tissue and blood from patients to test in the laboratory may help the study of cancer in the future.

PURPOSE: The purpose of this study is to collect and store samples of blood and tumor tissue from patients with osteosarcoma.

OBJECTIVES:

  • To collect biological specimens from patients with osteosarcoma at Children's Oncology Group (COG) institutions.
  • To provide a repository for long-term storage of osteosarcoma-related biological materials.
  • To make these specimens available to qualified researchers to understand the biology of osteosarcoma and correlate these results with the patients' clinical data.

OUTLINE: After the initial submission of blood samples, patients may undergo open or closed biopsy in order to obtain fresh and frozen tissue samples as well as paraffin embedded material. Patients who are enrolled at the time of initial diagnosis but then have a definitive surgery or develop recurrent disease may submit additional samples (paraffin block, frozen and fresh tumor tissue, or slides together with blood samples). Autopsy tumor samples may also be submitted.

Observational
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Sarcoma
Other: biologic sample preservation procedure
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
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DISEASE CHARACTERISTICS:

  • All osteosarcoma patients seen at COG institutions are eligible, including the following:

    • Newly diagnosed patients
    • Patients with recurrent disease who were not enrolled at the time of diagnosis
  • The following specimens from the initial biopsy (and/or definitive surgery if an up-front resection is performed) are required:

    • Paraffin embedded block OR 30 unstained slides
    • Pretreatment blood consisting of 5 mL serum, 10 mL plasma, and 10 mL heparinized whole blood
    • Fresh and frozen tumor specimens

PATIENT CHARACTERISTICS:

  • Not specified

PRIOR CONCURRENT THERAPY:

  • Patients are not required to enter a therapeutic study to enroll on this study
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United States,   Australia,   Canada,   New Zealand,   Puerto Rico
 
NCT00899275
CDR0000562538, COG-AOST06B1
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Children's Oncology Group
National Cancer Institute (NCI)
Study Chair: Richard Gorlick, MD Children's Hospital at Montefiore
National Cancer Institute (NCI)
November 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP