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Aerobic Training, Aerobic-resistance Training and Glucose Profile (CGMS) in Type 2 Diabetes (CGMSexercise)

This study has been completed.
Sponsor:
Information provided by:
Hospital de Clinicas de Porto Alegre
ClinicalTrials.gov Identifier:
NCT00887094
First received: April 22, 2009
Last updated: August 3, 2011
Last verified: August 2011
History of Changes

April 22, 2009
August 3, 2011
June 2009
March 2011   (final data collection date for primary outcome measure)
Reduction of the prevalence of hyperglycemic peaks during a 24-h period after a bout of aerobic or aerobic/resistance exercise in type 2 diabetes patients on metformin/diet therapy. [ Time Frame: 24h ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00887094 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Aerobic Training, Aerobic-resistance Training and Glucose Profile (CGMS) in Type 2 Diabetes
Acute and Subacute Effects of Aerobic Training vs Aerobic/Resistance Training Upon Glucose Profile Evaluated Through Continuous Glucose Monitoring System in Type 2 Diabetes

Many studies were already performed showing beneficial cardiovascular and metabolic effects of physical training for type 2 diabetic patients. However, glucose profile during and immediately after a short period of aerobic and/or resistance training was not studied yet. Continuous glucose monitoring system (CGMS) has now been added to the repertoire of technological devices useful in the management of patients with diabetes. Such monitoring enables clinicians to detect occult hypoglycemia and hyperglycemia not otherwise discernable with intermittent testing of blood glucose. The main aim of the present study is to investigate continuous blood glucose profile (using CGMS) over 72h, beginning 24h before and ending 24h after a single bout of aerobic or aerobic/resistance physical training in type 2 diabetic patients.

Many studies were already performed showing beneficial cardiovascular and metabolic effects of physical training for type 2 diabetic patients. However, glucose profile during and immediately after a short period of aerobic and/or resistance training was not studied yet. Continuous glucose monitoring system (CGMS) has now been added to the repertoire of technological devices useful in the management of patients with diabetes. Such monitoring enables clinicians to detect occult hypoglycemia and hyperglycemia not otherwise discernable with intermittent testing of blood glucose. The main aim of the present study is to investigate continuous blood glucose profile (using CGMS) over 72h, beginning 24h before and ending 24h after a single bout of aerobic or aerobic/resistance physical training in type 2 diabetic patients.
Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
  • Diabetes Mellitus, Type 2
  • Treatment
  • Exercise
  • Behavioral: Acute aerobic exercise
    Aerobic exercise (on a cycle ergometer, for 50 min)
    Other Name: There are no other names
  • Behavioral: Acute aerobic-resistance exercise
    Aerobic-resistance exercise (on a cycle ergometer plus strength training, for 50 min in total)
    Other Name: There are no other names
  • Experimental: Aerobic exercise
    One bout of aerobic physical training will be performed on a cycle ergometer for 50 min
    Intervention: Behavioral: Acute aerobic exercise
  • Experimental: Aerobic-resistance exercise
    One bout of aerobic-resistance physical training will be performed on a cycle ergometer added by a strenght training for 50 min (total)
    Intervention: Behavioral: Acute aerobic-resistance exercise
Figueira FR, Umpierre D, Ribeiro JP, Tetelbom PS, Henn NT, Esteves JF, Schaan BD. Accuracy of continuous glucose monitoring system during exercise in type 2 diabetes. Diabetes Res Clin Pract. 2012 Dec;98(3):e36-9. doi: 10.1016/j.diabres.2012.09.033. Epub 2012 Oct 4.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
14
April 2011
March 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Type 2 diabetic patients treated with diet and metformin, 35-65 years old

Exclusion Criteria:

  • Type 1 diabetic patients
  • Treatment with insulin or sulphonylureas or glitazones
  • Proliferative retinopathy
  • Severe autonomic neuropathy
  • Coronary artery disease
  • Baseline fasting plasma glucose>200 mg/dl
  • Peripheral artery disease
  • Amputation
  • Heart failure
  • Diabetic nephropathy
  • Renal failure
Both
35 Years to 65 Years
No
Contact information is only displayed when the study is recruiting subjects
Brazil
 
NCT00887094
08-180
Yes
Dr. Beatriz Schaan, Hospital de Clinicas de Porto Alegre
Hospital de Clinicas de Porto Alegre
Not Provided
Principal Investigator: Beatriz Schaan, PhD Hospital de Clinicas de Porto Alegre
Hospital de Clinicas de Porto Alegre
August 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP