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Evaluation of the Treatment of Recurrent Corneal Erosions by Anterior Stromal Puncture With Nd: YAG Laser

This study has been completed.
Sponsor:
Information provided by:
National Taiwan University Hospital
ClinicalTrials.gov Identifier:
NCT00816738
First received: August 31, 2008
Last updated: January 2, 2009
Last verified: December 2008
History of Changes

August 31, 2008
January 2, 2009
January 2008
February 2008   (final data collection date for primary outcome measure)
Cure rate of recurrent corneal erosions (frequency of attack and numbers of Nd: YAG laser treatment), intensity of pain relief and visual acuity. [ Time Frame: Before treatment, weekly after the treatment, and monthly after symptom relief ] [ Designated as safety issue: Yes ]
Same as current
Complete list of historical versions of study NCT00816738 on ClinicalTrials.gov Archive Site
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Evaluation of the Treatment of Recurrent Corneal Erosions by Anterior Stromal Puncture With Nd: YAG Laser
Evaluation of the Treatment of Recurrent Corneal Erosions by Anterior Stromal Puncture With Nd: YAG Laser

To evaluate the clinical outcomes in patients with recurrent corneal erosions who received anterior stromal puncture by use of neodymium:yttrium-aluminum-garnet (Nd:YAG) laser.

Participants: From 2000 to 2005, thirty-three eyes in 33 patients with unilaterally recurrent corneal erosions who showed poor response to conservative managements and were treated with Nd:YAG laser were studied.

Intervention: Anterior corneal stromal puncture with Nd:YAG laser was performed in the loosened epithelium or epithelial defect area. The causes and frequency of corneal erosions and the spot numbers and total energy of the Nd:YAG laser were recorded. Slit-lamp biomicroscopic examination, refraction, corneal topography, and times of laser were reviewed. A questionnaire regarding the preoperative and postoperative difference in the intensity of pain and frequency of corneal erosion was provided.

Main Outcome Measures: Rate of recurrence and pain assessment by numerical rating scale.
Observational
Observational Model: Cohort
Time Perspective: Retrospective
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Non-Probability Sample

to evaluate the clinical outcomes after anterior stromal puncture with Nd:YAG laser in a consecutive series of 33 eyes in 33 patients with unilaterally recurrent corneal erosion.
  • Recurrent Corneal Erosion
  • Trauma
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
33
March 2008
February 2008   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • patients with recurrent corneal erosions who showed poor response to conservative managements and were treated with Nd:YAG laser.

Exclusion Criteria:

  • Slit-lamp biomicroscopic examination in both eyes of patient showed any evidence of anterior basement membrane dystrophy.
Both
20 Years to 71 Years
No
Contact information is only displayed when the study is recruiting subjects
Taiwan
 
NCT00816738
200801035R
Yes
Yu-Chih Hou/Department of Ophthalmology, National Taiwan University Hospital, Organization: Department of Ophthalmology, National Taiwan University Hospital
National Taiwan University Hospital
Not Provided
Study Director: Yu-Chih Ho, MD Department of Ophthalmology, National Taiwan University Hospital
Principal Investigator: Tzu-Hsun Tsai, MD Department of Ophthalmology, National Taiwan University Hospital
Principal Investigator: Tzu-Yun Tsai, MD Department of Ophthalmology, National Taiwan University Hospital
National Taiwan University Hospital
December 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP