Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans

This study has been completed.
Sponsor:
Collaborator:
U.S. Army Medical Research and Materiel Command
Information provided by (Responsible Party):
James Baraniuk, MD, Georgetown University
ClinicalTrials.gov Identifier:
NCT00810225
First received: December 17, 2008
Last updated: February 24, 2014
Last verified: February 2014

December 17, 2008
February 24, 2014
August 2008
July 2011   (final data collection date for primary outcome measure)
Not Provided
Not Provided
Complete list of historical versions of study NCT00810225 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Study of Gulf War Illness (GWI) by Comparing GWI and Healthy Veterans
CNDP1 Polymorphisms in Gulf War Illness (GWI)

Determine if:

  • genetic differences of CNDP1 gene
  • the previously defined GWI/Chronic Fatigue Syndrome (GWI/CFS) cerebrospinal fluid proteome contents
  • psychometric
  • other variables can differentiate between veterans of the 1990-1991 Persian Gulf War who have autonomic, neurological and other symptoms and those without these complaints.
Not Provided
Observational
Observational Model: Case Control
Time Perspective: Cross-Sectional
Not Provided
Retention:   Samples With DNA
Description:

Plasma, serum, urine, and buccal swab samples retained for testing as described in protocol.

Non-Probability Sample

All veterans who served in the Armed Forces between August 1990 and July 1991

  • Gulf War Illness
  • Persian Gulf War Syndrome
Not Provided
  • 1
    GWI: veterans of the 1990-1991 Persian Gulf War who have autonomic, neurological and other symptoms
  • 2
    HC: healthy veterans of the 1990-1991 Persian Gulf War

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
516
July 2011
July 2011   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Evidence of military enlistment between August 1, 1990 and July 31, 1991, and deployment for 30 consecutive days to:

    • Persian Gulf waters and adjacent land areas
    • Other global locations
    • U.S. only
  • Status prior to 1990 and 1991:

    • Active duty
    • National Guard
    • Reserves

Exclusion Criteria:

  • Current active duty military personnel
  • Any one who was not active duty military personnel between August 1, 1990 and July 31, 1991
  • HIV/AIDS; pregnancy or lactation; potential hepatitis; drug addiction; chronic inflammatory, infectious, or autoimmune medical illnesses not associated with GWI; incarceration; dementia, other cognitive limitation; or reliance on a care-giver in order to respond to the questionnaires and other study tests.

Amputations of one or both hands and forearms will be permitted but hand grip tests will not be tested

Both
Not Provided
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00810225
2008-012, USAMRMC PR# W81XWH-07-1-0618, HRPO Log No. A-14542.1
No
James Baraniuk, MD, Georgetown University
Georgetown University
U.S. Army Medical Research and Materiel Command
Principal Investigator: James N Baraniuk, MD Georgetown University
Georgetown University
February 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP