Uremic Toxins in the Intensive Care Unit (ICU): Patients With Sepsis

This study is currently recruiting participants.
Verified February 2013 by University Hospital, Ghent
Sponsor:
Information provided by (Responsible Party):
University Hospital, Ghent
ClinicalTrials.gov Identifier:
NCT00752245
First received: September 12, 2008
Last updated: February 1, 2013
Last verified: February 2013

September 12, 2008
February 1, 2013
September 2008
March 2013   (final data collection date for primary outcome measure)
Registration of toxin removal efficiency [ Time Frame: During dialysis ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00752245 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Uremic Toxins in the Intensive Care Unit (ICU): Patients With Sepsis
Study of the Kinetics of Uremic Toxins in the ICU Patients With Acute Renal Failure, in Order to Optimize the Dialysis Dose: Patients With Sepsis/Multi-organ Failure

Study of the kinetics of uremic toxins in the ICU patients with acute renal failure, in order to optimize the dialysis dose: patients with sepsis/multi-organ failure. The sampling of blood and dialysate will be done during dialyses with different durations (4, 6 and 8h)

Not Provided
Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Crossover Assignment
Masking: Open Label
Primary Purpose: Treatment
  • Renal Failure
  • Multi Organ Failure
  • Procedure: Dialysis during 4 hours
    Blood and dialysate sampling
  • Procedure: Dialysis during 6 hours
    Blood and dialysate sampling
  • Procedure: Dialysis during 8 hours
    Blood and dialysate sampling
  • Experimental: 1
    Dialysis during 4 hours
    Intervention: Procedure: Dialysis during 4 hours
  • Active Comparator: 2
    Dialysis during 6 hours
    Intervention: Procedure: Dialysis during 6 hours
  • Active Comparator: 3
    Dialysis during 8 hours
    Intervention: Procedure: Dialysis during 8 hours
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
12
December 2013
March 2013   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • ICU patients with sepsis/multi-organ failure with acute renal failure
Both
18 Years and older
No
Contact: Sunny Eloot, PhD Sunny.eloot@ugent.be
Belgium
 
NCT00752245
2008/373
No
University Hospital, Ghent
University Hospital, Ghent
Not Provided
Principal Investigator: Raymond Vanholder, MD, PhD University Hospital, Ghent
University Hospital, Ghent
February 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP