A Study of the Association Between Tobacco Smoking and Bipolar Affective Disorder

This study has been completed.
Sponsor:
Information provided by (Responsible Party):
Anatoly Dr. Kreinin, Tirat Carmel Mental Health Center
ClinicalTrials.gov Identifier:
NCT00741299
First received: August 25, 2008
Last updated: July 25, 2012
Last verified: July 2012

August 25, 2008
July 25, 2012
August 2007
July 2009   (final data collection date for primary outcome measure)
Relationship between smoking and other factors including: bipolar subtype, current and past clinical status, illness severity,history of a suicide attempts, age of bipolar onset, gender, education, social class, economic status. [ Time Frame: One interview session ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00741299 on ClinicalTrials.gov Archive Site
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A Study of the Association Between Tobacco Smoking and Bipolar Affective Disorder
Association Between Tobacco Smoking and Bipolar Affective Disorder.Clinico-epidemiological, Cross-sectional, Retrospective Study.

The purpose of this study is to examine whether tobacco smoking is associated with bipolar affective disorder (severity of depressive and manic symptoms, presence of psychotic symptoms, history of a suicide attempts and other clinical features.)

An association exists between smoking and schizophrenia, independent of other factors and related to psychotic symptomatology. Only a few small descriptive studies have examined the prevalence and correlates of tobacco use among bipolar patients with conflicting results. Patients who smoke score higher on rating scales for psychotic symptoms than their non-smoking peers. While the association of smoking with psychotic symptomatology in schizophrenia is established, such association according to bipolar affective disorder has been reported in a few studies and remains unclear. Also a few studies reported about association of smoking with depressive and manic symptoms, and with suicidal behavior in bipolar patients. Thus further investigation of these issues is warranted.

Observational
Time Perspective: Retrospective
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Probability Sample

The sample will consist of all patients ascertained in database of Tirat Carmel Mental Health Center and Psychiatric Outpatients Clinic, Rambam Medical Center

Bipolar Disorder
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Kreinin A, Novitski D, Rabinowitz D, Weizman A, Grinshpoon A. Association between tobacco smoking and bipolar affective disorder: clinical, epidemiological, cross-sectional, retrospective study in outpatients. Compr Psychiatry. 2012 Apr;53(3):269-74. doi: 10.1016/j.comppsych.2011.04.063. Epub 2011 Jun 12.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
100
September 2009
July 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Age 18-65 male or female
  • DSM -IV criteria for bipolar I affective disorder
  • Ability and willingness to sign informed consent for participation in the study

Exclusion Criteria:

  • Unwillingness or inability to participate in the study
Both
18 Years to 65 Years
No
Contact information is only displayed when the study is recruiting subjects
Israel
 
NCT00741299
GKN2007, GKN2007
No
Anatoly Dr. Kreinin, Tirat Carmel Mental Health Center
Tirat Carmel Mental Health Center
Not Provided
Principal Investigator: Anatoly Kreinin, MD, PHD B. Rappaport Faculty of Medicine, Technion, Haifa
Principal Investigator: Anatoly Kreinin, MD, PhD B. Rappaport Faculty of Medicine, Technion, Haifa
Tirat Carmel Mental Health Center
July 2012

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP