Corrected Measurement of the Retinal Nerve Fiber Layer Thickness by Optic Disc Configuration With the Cirrus HD OCT

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2008 by Yonsei University.
Recruitment status was  Recruiting
Sponsor:
Information provided by:
Yonsei University
ClinicalTrials.gov Identifier:
NCT00741130
First received: August 25, 2008
Last updated: NA
Last verified: August 2008
History: No changes posted

August 25, 2008
August 25, 2008
July 2008
October 2008   (final data collection date for primary outcome measure)
the Cirrus HD OCT [ Time Frame: when the OCT images are taking ] [ Designated as safety issue: No ]
Same as current
No Changes Posted
  • automated visual field [ Time Frame: when the OCT images are taking ] [ Designated as safety issue: No ]
  • red-free fundus photo [ Time Frame: when the OCT images are taking ] [ Designated as safety issue: No ]
  • refractive errors [ Time Frame: when the OCT images are taking ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Corrected Measurement of the Retinal Nerve Fiber Layer Thickness by Optic Disc Configuration With the Cirrus HD OCT
Corrected Measurement of the Retinal Nerve Fiber Layer Thickness by Optic Disc Configuration With the Cirrus HD OCT

Because the measurement of the retinal nerve fiber layer thickness is very sensitive to the position of measurement, it may be incorrect in patients with the tilted disc. In the present study, the corrected RNFL thickness by the optic nerve head configuration using the Cirrus HD OCT will be evaluated. If the corrected RNFL thickness is more sensitive to detect the localized RNFL defect, the present software should be upgrade to reflect the optic nerve head configuration.

Finding the localized retinal nerve fiber layer (RNFL) defect and measuring the RNFL thickness are two main issues for early glaucoma detection. A recently developed imaging device, the Cirrus HD OCT, offers more detailed informations about retina architecture including optic nerve head. To calculate the RNFL thickness, the software of the Cirrus HD OCT supposes an ideal optic nerve head. However, in the cases with not ideal optic disc configuration, the measurement of the RNFL thickness is not correct. Because the measurement of the RNFL thickness is extremely sensitive to the position of measurement, patients with the tilted disc are in danger of misdiagnosis. In the present study, we want to correct the RNFL thickness measurement according to the optic nerve head configuration using the Cirrus HD OCT. If the corrected RNFL thickness is more sensitive to detect the localized RNFL defect, the present software should be upgrade to reflect the optic nerve head configuration.

Observational
Observational Model: Case-Only
Time Perspective: Cross-Sectional
Not Provided
Not Provided
Non-Probability Sample

Volunteers of our opthalmologic clinic

  • Glaucoma
  • Myopia
Not Provided
  • C
    normal volunteers
  • G
    glaucoma patients
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Recruiting
50
January 2009
October 2008   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • normal controls or glaucoma patients
  • signal intensity of the OCT image > 8
  • cooperative subjects

Exclusion Criteria:

  • spherical equivalent refractive errors > +4 diopters or < -4 diopters
  • significant media opacity
  • previous intraocular surgery
Both
18 Years to 70 Years
Yes
Contact: Gong Je Seong, MD, PhD 82-2-2019-3441 gjseong@yuhs.ac
Korea, Republic of
 
NCT00741130
3-2008-0076
Yes
Gong Je Seong, Yonsei University College of Medicine
Yonsei University
Not Provided
Study Chair: Gong Je Seong, MD, PhD Yonsei University
Yonsei University
August 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP