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Cognitive Behavioural Therapy of Early Dementia (KORDIAL)

This study has been completed.
Sponsor:
Collaborators:
University of Leipzig
Zentralinstitut für seelische Gesundheit, Abteilung Gerontopsychiatrie J5,
Humboldt-Universität zu Berlin
Information provided by:
Technische Universität München
ClinicalTrials.gov Identifier:
NCT00735046
First received: August 13, 2008
Last updated: January 13, 2011
Last verified: July 2008
History of Changes

August 13, 2008
January 13, 2011
April 2008
Not Provided
Functional ability in the everyday context [ Time Frame: Baseline, post treatment, 6 months post treatment ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00735046 on ClinicalTrials.gov Archive Site
Quality of life, depression, neuro-psychiatric symptoms [ Time Frame: Same as for primary outcome ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Cognitive Behavioural Therapy of Early Dementia
Cognitive Behavioural Resource-based Therapy of Early Dementia in the Everyday Setting

A randomized, controlled, parallel-group trial to evaluate the efficacy of a cognitive behavioral therapy for patients with early dementia.

The KORDIAL study is a randomized, controlled, parallel-group trial evaluating the efficacy of a cognitive behavioral therapy for patients at the early stage of Alzheimer's disease. The 3-month experimental intervention consists of 12 individual sessions with regular involvement of carers or other patient proxies. Strategies for improving the patient's coping ability and for enhancing their psychological well-being are combined. The primary outcome criterion is functioning in the everyday context after completion of the intervention and after another 6 months. The control condition will be treatment as usual. The study will be conducted in 5 university outpatient units and in 5 specialist offices.
Observational
Time Perspective: Prospective
Not Provided
Retention:   None Retained
Description:

not required
Non-Probability Sample

Patients referred to memory clinics and specialist (psychiatrist, neurologist) offices
Dementia
  • Behavioral: Cognitive behavioral therapy for early Alzheimer's disease
    12 weekly individual sessions, total duration 3 months, regular involvement of patient's proxy ever second session. Intervention is manualized but is flexible with regard to individual resources and needs.
  • Other: Control
    Patients and proxies who are assigned to treatment as usual
  • 1
    Intervention
    Intervention: Behavioral: Cognitive behavioral therapy for early Alzheimer's disease
  • 2
    control
    Intervention: Other: Control

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
200
April 2010
Not Provided

Inclusion Criteria:

  • Mild dementia (MMSE > 21) in Alzheimer's disease (ICD-10), proxy available

Exclusion Criteria:

  • Acute of unstable psychiatric or physical disease, proxy unavailable
  • Participation in another trial
Both
18 Years to 95 Years
No
Contact information is only displayed when the study is recruiting subjects
Germany
 
NCT00735046
KOR-683-KUR-0000-I
Yes
Alexander Kurz M.D., klinikum rechts der Isar
Technische Universität München
  • University of Leipzig
  • Zentralinstitut für seelische Gesundheit, Abteilung Gerontopsychiatrie J5,
  • Humboldt-Universität zu Berlin
Study Director: Alexander Kurz, MD Klinikum rechts der Isar
Technische Universität München
July 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP