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Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified August 2009 by Tufts University.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
Tufts University
ClinicalTrials.gov Identifier:
NCT00721643
First received: July 22, 2008
Last updated: August 24, 2009
Last verified: August 2009
History of Changes

July 22, 2008
August 24, 2009
July 2008
March 2009   (final data collection date for primary outcome measure)
Plasma quercetin [ Time Frame: 0, 30, 60, 100, 180, 240, 300, 360, 420 & 480 min ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00721643 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)
Absorption Kinetics of Polyphenols in Angel's Plant (Angelica Keiskei)

The absorption kinetics of polyphenols in angel's plant (Angelica keiskei), which is a dark green leafy vegetable rich in antioxidant nutrients, will be determined in older adults in this pilot study.
Not Provided
Interventional
Phase 0
Allocation: Non-Randomized
Endpoint Classification: Bio-availability Study
Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Basic Science
Oxidative Stress
  • Dietary Supplement: angel's plant (Angelica keiskei)
    Healthy control, one time dose of 5g dry power of Angelica keiskei
  • Dietary Supplement: Angel's plant (Angelica keiskei)
    Metaboic syndrome subjects, one time dose of 5g dry powder of angel's plant (Angelica keiskei)
  • Experimental: 1
    Healthy control, 5g dry power of angel's plant (Angelica keiskei)
    Intervention: Dietary Supplement: angel's plant (Angelica keiskei)
  • Experimental: 2
    Metabolic syndrome, 5g dry powder of angel's plant (Angelica keiskei)
    Intervention: Dietary Supplement: Angel's plant (Angelica keiskei)
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
10
December 2010
March 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Healthy subjects (>60 yr, n=5)
  • subjects with metabolic syndrome (>60 yr, n=5)

  • Subjects who has

    • high fasting plasma glucose (>5.6 mmol/L),
    • central obesity (waist-hip ratio, >0.9 for men, >0.85 for women)
    • either high blood pressure (>130/85 mmHg) or high triacylglycerol (>1.7 mmol/L) will be selected to have metabolic syndrome.
  • normal hematological parameters, normal serum albumin, normal liver function, and normal kidney function
  • no history of smoking or alcoholism.

Exclusion Criteria:

  • consume >7 alcoholic drinks/wk
  • taking cholesterol medication or hormone replacement
Both
60 Years and older
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00721643
HNRCA2580, BioGreen 20070301034009
No
Kyung-Jin Yeum, Scientist, Jean Mayer USDA-Human Nutrition Research Center on Aging at Tufts University
Tufts University
Not Provided
Principal Investigator: Kyung-Jin Yeum, Ph.D. Tufts Medical Center
Tufts University
August 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP