Prospective Registry of Outcomes and Management of Acute Ischaemic Syndromes

This study has been completed.
Sponsor:
Collaborators:
Sanofi
Bristol-Myers Squibb
Information provided by:
Royal Brompton & Harefield NHS Foundation Trust
ClinicalTrials.gov Identifier:
NCT00716352
First received: July 15, 2008
Last updated: NA
Last verified: July 2008
History: No changes posted

July 15, 2008
July 15, 2008
March 2004
Not Provided
Adherence to the educational programme measured by the frequency of use of the evidence based treatments: Aspirin, Heparin, Clopidogrel, Beta blockers, Statins.
Same as current
No Changes Posted
  • Comparison of investigations and tests
  • Use of other treatments
  • Counselling for lifestyle changes
  • Referral to smoking cessation clinics
  • Cardiac rehabilitation
  • Compliance to treatment at 6 months
  • Comparison of clinical events at 6 months
Same as current
Not Provided
Not Provided
 
Prospective Registry of Outcomes and Management of Acute Ischaemic Syndromes
Prospective Registry of Outcomes and Management of Acute Ischaemic Syndromes

This is a multi-centre UK study designed to evaluate if an educational intervention programme delivered to health care professionals can improve the use of evidence based treatments in the management of patients admitted to hospital with non-ST elevation Acute Coronary Syndrome. A total of 38 centres participated, half received the educational intervention. Patients were followed to hospital discharge. Patients were followed up at 6 months. Longer term follow up through the Office Of National Statistics will be performed.

This is a multi-centre UK study designed to evaluate if an educational intervention programme delivered to health care professionals can improve the use of evidence based treatments in the management of patients admitted to hospital with non-ST elevation Acute Coronary Syndrome. A total of 38 centres participated. A cluster randomised method was used and half of centres received the educational intervention. Patients were followed to hospital discharge. Patients were followed up at 6 months and longer term follow up for mortality will be performed through the national databases.

Interventional
Not Provided
Allocation: Randomized
Intervention Model: Parallel Assignment
Primary Purpose: Health Services Research
  • Acute Coronary Syndromes
  • Coronary Artery Disease
Behavioral: Educational intervention programme
Not Provided
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
1340
November 2005
Not Provided

Inclusion Criteria:All patients admitted to the hospital (either through casualty or directly to the wards), with a good clinical history of an acute coronary syndrome with one or more of the following:

  1. Ischaemic changes on the admission ECG (including patients with bundle branch block)
  2. Elevated Troponin or cardiac enzymes on admission
  3. Normal ECGs but with evidence of pre-existing coronary artery disease i.e., evidence of a prior history of MI, coronary revascularisation, coronary angiography demonstrating the presence of significant coronary stenosis or a stress test demonstrating ischaemia (treadmill, echo or nuclear scan)

Written informed consent

Exclusion Criteria:

  1. Patients with persistent ST elevation >1mm in two or more contiguous leads on the ECG.
  2. Patients treated with thrombolytic therapy, or for whom thrombolytic therapy was considered on admission.
Both
Not Provided
No
Contact information is only displayed when the study is recruiting subjects
United Kingdom
 
NCT00716352
MREC/03/10/48
Not Provided
Not Provided
Royal Brompton & Harefield NHS Foundation Trust
  • Sanofi
  • Bristol-Myers Squibb
Principal Investigator: Marcus Flather Royal Brompton & Harefield NHS Trust, Imperial College London
Royal Brompton & Harefield NHS Foundation Trust
July 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP