Efficacy of Transference-Focused Psychotherapy for Borderline Personality Disorder

The recruitment status of this study is unknown because the information has not been verified recently.
Verified July 2008 by University Hospital Muenster.
Recruitment status was  Active, not recruiting
Sponsor:
Information provided by:
University Hospital Muenster
ClinicalTrials.gov Identifier:
NCT00714311
First received: July 9, 2008
Last updated: February 13, 2009
Last verified: July 2008

July 9, 2008
February 13, 2009
October 2004
February 2009   (final data collection date for primary outcome measure)
  • Drop-out [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • Suicidality (suicide attempts) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
Remission of borderline personality disorder according to the criteria of DSM-IV. [ Time Frame: 1 year ] [ Designated as safety issue: No ]
Complete list of historical versions of study NCT00714311 on ClinicalTrials.gov Archive Site
  • Psychosocial Functioning (Global Assessment of Functioning, GAF-Score) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • Level of personality organization (Structured Interview for Personality Organization, STIPO) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • Number of self-harming acts [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • Self-assessment of psychopathology (BDI, STAI, BSI) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • Attachment style and Reflective Function (Adult Attachment Interview, AAI) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • Borderline symptomatology (DSM-IV criteria) [ Time Frame: 1 month ] [ Designated as safety issue: No ]
  • Psychosocial Functioning (Global Assessment of Functioning, GAF-Score) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • Level of personality organization (Structured Interview for Personality Organization, STIPO) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • Number of suicide attempts [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • Number of self-harming acts [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • Self-assessment of psychopathology (BDI, STAI, BSI) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • Attachment style and Reflective Function (Adult Attachment Interview, AAI) [ Time Frame: 1 year ] [ Designated as safety issue: No ]
Not Provided
Not Provided
 
Efficacy of Transference-Focused Psychotherapy for Borderline Personality Disorder
A Randomized-Controlled Trial of Transference-Focused Psychotherapy vs. Treatment by Experienced Community Psychotherapists for Borderline Personality Disorder

The purpose of this study is to find out whether Transference-Focused Psychotherapy (TFP) is effective in the treatment of Borderline Personality Disorder.

Borderline personality disorder represents a sever clinical condition that affects 1-2% of the community and is characterized by a pervasive instability of interpersonal relationships, self-image, and affects, as well as a marked impulsivity; up to 10% of the patients commit suicide.

Transference-Focused Psychotherapy (TFP) is one psychotherapeutic approach among five that have been manualized and evaluated in RCTs. So far, TFP has not been compared to a control condition which is a crucial step in the evaluation of the efficacy of a psychosocial intervention.

This study is an RCT that compares one year of outpatient TFP to treatment by experienced community psychotherapists for borderline personality disorder.

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Single Blind (Outcomes Assessor)
Primary Purpose: Treatment
Borderline Personality Disorder
  • Behavioral: Transference-Focused Psychotherapy
    Outpatient psychotherapy according to the treatment manual, sessions of 50 minutes twice per week
  • Behavioral: treatment by experienced community psychotherapists
    Outpatient psychotherapy in private practices or outpatient units of psychiatric hospitals. Licensed psychotherapists with experience and special interest in the treatment of borderline patients are treating according to the method they have learned.
  • Active Comparator: TFP
    Transference-Focused Psychotherapy
    Intervention: Behavioral: Transference-Focused Psychotherapy
  • Active Comparator: ECP
    treatment by experienced community psychotherapists
    Intervention: Behavioral: treatment by experienced community psychotherapists

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
104
February 2012
February 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Written informed consent to the participation in the study
  • Diagnosis of BPD according to DSM-IV as assessed using the SCID-II
  • Age between 18 and 45 years
  • Sufficient knowledge of the German language

Exclusion Criteria:

  • Diagnosis of schizophrenia, bipolar disorder, severe substance abuse, organic pathology, or mental retardation according to DSM-IV as assessed using the SCID-I
  • Diagnosis of antisocial personality disorder according to DSM-IV as assessed using the SCID-II
Female
18 Years to 45 Years
No
Contact information is only displayed when the study is recruiting subjects
Austria,   Germany
 
NCT00714311
1106/04, 10636, DPG0802
No
Stephan Doering, MD, University of Muenster, Germany
University Hospital Muenster
Not Provided
Principal Investigator: Stephan Doering, MD University of Muenster, Germany
University Hospital Muenster
July 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP