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Speech and Language Therapy After Stroke

This study is currently recruiting participants.
Study NCT00713050.   Last updated on October 17, 2008.   Information provided by National Institute on Deafness and Other Communication Disorders (NIDCD)

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Descriptive Information Fields
Brief Title  Speech and Language Therapy After Stroke
Official Title  Neurophysiological Measurement in Aphasia Treatment
Brief Summary

Our overall goal is to advance the state of functional brain imaging in aphasia, and then to apply the method to an intensive, imitation-based treatment for non-fluent aphasia.

Detailed Description
Study Phase
Study Type  Interventional
Study Design  Treatment, Randomized, Double Blind (Subject, Outcomes Assessor), Single Group Assignment
Primary Outcome Measure  changes in scores on Western Aphasia Battery [ Time Frame: Four months ] [ Designated as safety issue: No ]
Secondary Outcome Measure 
Condition  Ischemic Stroke
Intervention  Behavioral: Imitate Therapy
MEDLINE PMIDs
Links
Recruitment Information Fields
Recruitment Status  Recruiting
Enrollment  57
Start Date  August 2007
Completion Date
Eligibility Criteria 

Inclusion Criteria:

  1. Single ischemic infarction in the MCA territory involving the cerebral cortex (confirmed by CT or MRI)
  2. Aphasia
  3. Visual attention and language comprehension sufficient to perform imitation fMRI tasks
  4. Right handed (prior to stroke)

Exclusion Criteria:

Exclusions to the study are people with cardiac pacemakers, claustrophobia, neurosurgical clips, or cognitive impairments too severe to permit cooperation with cognitive tasks in an MRI scanner.

Gender Both
Ages
Accepts Healthy Volunteers No
Contacts ††
Contact: Blythe Buchhols     773-834-7780     bbuchholz@uchicago.edu    
Location Countries  United States
Administrative Information Fields
NCT ID  NCT00713050
Organization ID 5R01DC7488-3
Secondary IDs ††
Study Sponsor  National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborators †† Rehabilitation Institute of Chicago
Investigators 
Principal Investigator:     Steven Small, M.D.,Ph.D.     University of Chicago    
Information Provided By National Institute on Deafness and Other Communication Disorders (NIDCD)
Verification Date October 2008
First Received Date  July 9, 2008
Last Updated Date October 17, 2008

 †    Required WHO trial registration data element.
††   WHO trial registration data element that is required only if it exists.




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