Impact of Left Atrial Function on Postoperative Atrial Fibrillation

This study has been completed.
Sponsor:
Information provided by:
Florence Nightingale Hospital, Istanbul
ClinicalTrials.gov Identifier:
NCT00646997
First received: March 26, 2008
Last updated: June 27, 2008
Last verified: June 2008

March 26, 2008
June 27, 2008
March 2008
May 2008   (final data collection date for primary outcome measure)
Velocity vector imaging derived left atrial segmenter function, Tissue doppler derved left atrial segmenter function, conventional analysis of atrial function by 2D and pulsed wave echocardiography. [ Time Frame: April 2008 ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00646997 on ClinicalTrials.gov Archive Site
Not Provided
Not Provided
Not Provided
Not Provided
 
Impact of Left Atrial Function on Postoperative Atrial Fibrillation
Impact Of Velocity Vector Imaging, Tissue Doppler Imaging, Conventional Echocardiography And P Wave Dispertion In Evaluating Post-Operative Atrial Fibrillation After Coronary Bypass Graft Surgery

We aimed to demonstrate the impact of left atrial functions which were evaluated by three different echocardiographic modalities , on postoperative atrial fibrillation.

Postoperative atrial fibrillation after coronary artery bypass greft operation (CABG) is major complication with a prevalence of 10-50%. Although the men mechanism is not known, in recent studies, age and left atrial function have been demonstrated as the most responsible factors. Velocity vector imaging (VVI) is a new modality which may give accurate and detailed information on both left atrial segmental and global function. In this study, our aim was to assess preoperative left atrial function by using three different echocardiographic modalities, VVI, tissue Doppler imaging and conventional echocardiography and evaluate the relation between the left atrial functions and the development of post-operative atrial fibrillation after CABG.

Observational
Observational Model: Case-Crossover
Time Perspective: Prospective
Not Provided
Not Provided
Probability Sample

Tertiary care clinic

Atrial Fibrillation
Not Provided
  • 1
    Patients with postoperative atrial fibrillation
  • 2
    Patients without postoperative atrial fibrillation.
1-Leung JM, Bellows WH, Schiller NB. Impairment of left atrial function predicts post-operative atrial fibrillation after coronary artery bypass graft surgery. European H J. 2004,25,1836-1844 2-Nakai T , Lee R, Schiller N, et al. The relative importance of left atrial function versus dimension in predicting atrial fibrilation after coronary bypass graft surgery. Am H Journal. 2002; 143:181-6

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
80
May 2008
May 2008   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • 1Coronary artery disease evidenced by coronary angiography
  • 2Patients with a decision of undergoing elective coronary artery bypass greft operation
  • 3Sinus rhythm in electrocardiography

Exclusion Criteria:

  • 1Rheumatic valve disease
  • 2Having prosthetic valve
  • 3CABG accompanied by other cardiac interventions (such as valvular surgery, ASD closure...etc)
  • 4Left ventricular l ejection fraction <40%
  • 5Mild to moderate mitral stenosis or regurgitation
  • 6Having atrial fibrillation or a history of atrial fibrillation attach during the last two weeks.
  • 7Congenital heart disease
  • 8Chronic liver disease
  • 9Chronic renal disease
  • 10Malignancy
Both
30 Years to 80 Years
No
Contact information is only displayed when the study is recruiting subjects
Turkey
 
NCT00646997
YT1977/2
Yes
Prof.Dr.Saide Aytekin, T.C. Istanbul Bilim University, Florence Nightingale Hospital
Florence Nightingale Hospital, Istanbul
Not Provided
Study Director: Saide Aytekin, Professor T.C. Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology
Florence Nightingale Hospital, Istanbul
June 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP