A Comparison of Hemorrhagic and Ischemic Strokes Among Blacks and Whites (GCNKSS)

This study is ongoing, but not recruiting participants.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Brett Kissela, University of Cincinnati
ClinicalTrials.gov Identifier:
NCT00642213
First received: March 19, 2008
Last updated: February 25, 2013
Last verified: February 2013

March 19, 2008
February 25, 2013
July 1993
June 2014   (final data collection date for primary outcome measure)
mRS [ Time Frame: 30 days ] [ Designated as safety issue: No ]
modified Rankin Scale
Not Provided
Complete list of historical versions of study NCT00642213 on ClinicalTrials.gov Archive Site
mortality [ Time Frame: 1 year ] [ Designated as safety issue: No ]
Not Provided
Not Provided
Not Provided
 
A Comparison of Hemorrhagic and Ischemic Strokes Among Blacks and Whites
A Comparison of Hemorrhagic and Ischemic Strokes Among Blacks and Whites: A Population-Based Study in Cincinnati, Ohio

Our primary goal is to study temporal trends in the incidence rate, causes, treatment, and outcome of stroke among a large biracial metropolitan population of 1,349,351, of whom 215,611 (15%) are black (2000 Census). Such data are critical for the planning, intervention, and evaluation of public health efforts to decrease the mortality and morbidity due to stroke in the United States.

For calendar years 1993-94, 1999, 2005, and 2010 we will identify every hospitalized or autopsied stroke and transient ischemic attack (TIA) at all regional hospitals in our region. We will also estimate the number of non-hospitalized strokes and TIAs by screening for potential cases at more than 100 outpatient sites throughout five counties in Greater Cincinnati/Northern Kentucky. We plan to identify and abstract detailed information from the medical record for every potential case. These results will be compared with data from all stroke patients identified by similar methodology in all study periods. In addition, we have interview 500 ischemic stroke patients and/or their families(each study year period starting in 1999), to obtain detailed information including demographic information, functional outcome and quality of life, access to and type of rehabilitation therapy, social support, caregiver availability and health status, access to post-hospital care, health insurance status, current health status, medications, prior risk factors, and knowledge about stroke signs and symptoms. We will also obtain genetic material via a blood sample.

Not Provided
Observational
Observational Model: Cohort
Time Perspective: Prospective
Not Provided
Retention:   Samples With DNA
Description:

In 2010 we have a prospectively collected a cohort of 516 of which 396 provided a blood sample for DNA to be stored at the University of Cincinnati. We have 450 samples stored from the 2005 cohort.

Non-Probability Sample

Prospective cohort:Ischemic stroke patient in 1999/2005/2010 that resides in the GCNK area.

  • Ischemic Stroke
  • TIA
  • Hemorrhage
Not Provided
  • 1
    We prospectively collected 450(1999), 502(2005), and 512(2010) ischemic stroke patients who agreed to participate and also most provided a sample for DNA. The cohort data consists of a baseline interview, medical record abstraction and various timeframes of followup interviews from 3m to 3yrs.
  • 2
    The second part of the study is a retrospective medical record review of all potential ischemic strokes, TIAs, and Hemorrhagic strokes in our 5 county region that occurred all study years.
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Active, not recruiting
516
June 2014
June 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • ischemic stroke
  • occurred in 1999/2005/2010
  • >18 years old
  • resides in 5 county region

Exclusion Criteria:

  • <18 years old
  • resides outside 5 county region
  • inability to consent or have legal proxy consent
Both
18 Years and older
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00642213
NS30678, NIH GRANT:NS30678
No
Brett Kissela, University of Cincinnati
University of Cincinnati
National Institute of Neurological Disorders and Stroke (NINDS)
Principal Investigator: Brett M Kissela, MD University of Cincinnati
University of Cincinnati
February 2013

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP