The Effect of Myopic Optical Defocus on the Humphrey Matrix 30-2 Test

This study has been completed.
Sponsor:
Information provided by:
Samsung Medical Center
ClinicalTrials.gov Identifier:
NCT00638430
First received: March 12, 2008
Last updated: NA
Last verified: March 2008
History: No changes posted

March 12, 2008
March 12, 2008
March 2007
October 2007   (final data collection date for primary outcome measure)
mean defect [ Time Frame: 15 minutes ] [ Designated as safety issue: No ]
Same as current
No Changes Posted
Not Provided
Not Provided
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The Effect of Myopic Optical Defocus on the Humphrey Matrix 30-2 Test
The Effect of Myopic Optical Defocus on the Humphrey Matrix 30-2 Test

The purpose of this study is to examine the effect of the myopic optical defocus on the Humphrey Matrix 30-2 test.

The Humphery Matrix (Zeiss, Dublin, California, USA; in cooperation with Welch Allyn, Skaneateles, New York, USA), which is a recently developed version of FDT perimetry, showed more improved technology to detect early glaucomatous damage. The user's guide for the Humphrey Matrix (Humphrey® matrix visual field instrument user's guide. Zeiss, Dublin, California, USA; in cooperation with Welch Allyn, Skaneateles, New York, USA; 2003) suggests that myopic refractive errors more than -3.0 D need to be corrected before the 30-2 test. However, the proper correction of the optical defocus is not always easy because of a lack of trial frame.

The purpose of the present study is twofold. At first, the influence of the low-grade myopia on the Humphery Matrix 30-2 test will be evaluated and compared to the effect of moderate-grade myopia. Secondly, the influence of myopic optical defocus and the glaucomatous visual field damage on the pattern deviation plot change according to the severity of glaucomatous visual field damage will be estimated.

Observational
Observational Model: Case-Only
Time Perspective: Prospective
Not Provided
Not Provided
Non-Probability Sample

tertiary care clinic

Myopia
Not Provided
  • 1
    low myopic group
  • 2
    moderate myopic group
Anderson AJ, Johnson CA. Frequency-doubling technology perimetry and optical defocus. Invest Ophthalmol Vis Sci. 2003 Sep;44(9):4147-52.

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
40
March 2008
October 2007   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • intra-ocular pressure 23 or higher
  • suspicious glaucomatous optic disc change
  • suspicious defect of retinal nerve fiber layer
  • or eyes with various degrees of glaucoma

Exclusion Criteria:

  • a high myopic eye (SE more than -6.0 D)
  • moderate to severe cataract
  • evidence of diabetic or hypertensive retinopathy
  • macular disease
  • intra-ocular inflammation
  • history of intraocular surgery and any other ocular lesion that could have an influence on the perimetry result
Both
27 Years to 61 Years
Yes
Contact information is only displayed when the study is recruiting subjects
Korea, Republic of
 
NCT00638430
Humphrey30-2
No
Changwon Kee, Department of Ophthalmology, Samsung Medical Center,
Samsung Medical Center
Not Provided
Study Chair: Changwon Kee, M.D. Department of Ophthalmology, Samsung Medical Center,
Samsung Medical Center
March 2008

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP