Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders - Tabular View

Tracking Information

First Received Date ^ICMJE

March 3, 2008

Last Updated Date

March 1, 2009

Start Date ^ICMJE

May 2007

Primary Completion Date

January 2009 (final data collection date for primary outcome measure)

Current Primary Outcome Measures ^ICMJE

Original Primary Outcome Measures ^ICMJE

Change History

Complete list of historical versions of study NCT00631605 on ClinicalTrials.gov Archive Site

Current Secondary Outcome Measures ^ICMJE

Original Secondary Outcome Measures ^ICMJE

Descriptive Information

Brief Title ^ICMJE

Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders

Official Title ^ICMJE

Studies of Neuroendocrine and Energy Metabolism in Patients With Eating Disorders

Brief Summary

This study aims to investigate neuroendocrine, autonomic functioning, and energy metabolism in patients with eating disorder and their relationships with psychopathology of eating disorders (eating patterns, depression, and personality) in these patients.

Detailed Description

The study subjects include female patients with DSM-IV diagnosis of AN (n = 30), BN (n = 60) and age-controled normal subjects (n = 30). They will receive a clinical interview and are asked to complete several self-administered questionnaires which included eating-related questionnaires, general psychological functioning scales and personality scales. After overnight fast, each subject undergoes a blood sample collection for neuroendocrine examination, body composition examination using BIA method, basal metabolic rate measurement by indirect calorimetry, and ECG in the morning between 0800 and 0900. Clinical patients would be asked to repeat filling the self-rating scales, weight and body fat measurement, as well as blood drawing again 2 months after treatment.

Study Phase

Study Type ^ICMJE

Observational

Study Design ^ICMJE

Case Control, Cross-Sectional

Condition ^ICMJE

Anorexia Nervosa
Bulimia Nervosa

Intervention ^ICMJE

Study Arms / Comparison Groups

Publications *

* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information

Recruitment Status ^ICMJE

Completed

Enrollment ^ICMJE

112

Completion Date

January 2009

Primary Completion Date

January 2009 (final data collection date for primary outcome measure)

Eligibility Criteria ^ICMJE

Inclusion Criteria:

Subjects who fulfilled DSM-IV diagnosis of anorexia nervosa or bulimia nervosa
Normal controls

Exclusion Criteria:

Any major psychiatric disorders
Use of psychoactive medications
Drug and alcohol abuse
Medical problems (cardiovascular condition and endocrine disorders)

Gender

Both

Ages

Accepts Healthy Volunteers

Yes

Contacts ^ICMJE

Contact information is only displayed when the study is recruiting subjects

Location Countries ^ICMJE

Taiwan

Administrative Information

NCT ID ^ICMJE

NCT00631605

Responsible Party

Mei-Chih Tseng/Attending psychiatrist, National Taiwan University Hospital

Study ID Numbers ^ICMJE

200705061R

Study Sponsor ^ICMJE

National Taiwan University Hospital

Collaborators ^ICMJE

Investigators ^ICMJE

Principal Investigator:

Mei-Chih Tseng, MD, Msc

National Taiwan University Hospital

Information Provided By

National Taiwan University Hospital

Verification Date

March 2009

^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP