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Day of Embryo Transfer for Patients Undergoing In Vitro Fertilization

This study has been completed.
Sponsor:
Information provided by:
Stanford University
ClinicalTrials.gov Identifier:
NCT00615771
First received: February 1, 2008
Last updated: July 21, 2011
Last verified: July 2011
History of Changes

February 1, 2008
July 21, 2011
January 2007
March 2009   (final data collection date for primary outcome measure)
Pregnancy rates [ Time Frame: 1 year ] [ Designated as safety issue: No ]
Pregnancy rates
Complete list of historical versions of study NCT00615771 on ClinicalTrials.gov Archive Site
  • Live birth rates [ Time Frame: 1 year ] [ Designated as safety issue: No ]
  • Multiple gestation rates [ Time Frame: 1 year ] [ Designated as safety issue: Yes ]
  • Live birth rates
  • Multiple gestation rates
Not Provided
Not Provided
 
Day of Embryo Transfer for Patients Undergoing In Vitro Fertilization
Embryo Transfer on Day 2 vs. Day 3 After Oocyte Retrieval in Patients Who Plan to Replace All Embryos After an In Vitro Fertilization Cycle

We are examining whether pregnancy rates differ based on day of embryo transfer in patients who replace all available embryos after an IVF cycle. Patients must be undergoing IVF treatment at Stanford University and patients will not receive compensation for their participation (no medical costs covered or patient payment for participation).

The decision on the number of embryos to transfer after an IVF cycle is based on the number of available embryos, the quality of the embryos, the patient's age, and the goal of limiting multiple gestations. Stanford Fertility Center and most IVF centers examine the embryos on the third day after oocyte (egg) retrieval to select for the best quality embryos to transfer, and depending on quality, the remaining embryos are frozen to be used in the future. Patients with a limited number of embryos, those that plan to replace all available embryos after an IVF cycle, do not need to wait until the third day after oocyte retrieval to select embryos, and may replace the embryos on the second day after the oocyte retrieval. We are examining whether pregnancy rates differ among these patients based on the day of embryo transfer (Day 2 vs. Day3). Patients must be undergoing IVF treatment at Stanford University and patients will not receive compensation for their participation (no medical costs covered or patient payment for participation).
Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Infertility
Procedure: Day of embryo transfer
Women receive their embryo transfer 1 day earlier than standard of care.
  • Experimental: Day 2 embryo transfer
    Embryos are transferred 2 days after fertilization
    Intervention: Procedure: Day of embryo transfer
  • Active Comparator: Day 3 embryo transfer
    Standard of care for women undergoing IVF with a limited number of embryos is to transfer all embryos on Day 3 after fertilization
    Intervention: Procedure: Day of embryo transfer
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
242
March 2009
March 2009   (final data collection date for primary outcome measure)

Inclusion Criteria:

Patients undergoing fresh IVF cycle at Stanford Fertility Center who plan on replacing all available embryos.

Exclusion Criteria:

Patients that do not meet above criteria.
Female
18 Years to 50 Years
No
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00615771
SU-01312008-991
Yes
Ruth Lathi, Principle Investigator, Stanford University School of Medicine
Stanford University
Not Provided
Principal Investigator: Lora K Shahine Stanford University
Stanford University
July 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP