Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS) - Tabular View

Home

Study Topics

Glossary


	Full Text View


	Tabular View


	Contacts and Locations


	Related Studies

Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)

This study has been completed.
Information provided by University of California, Irvine

This Tabular View shows the required WHO registration data elements as marked by ^†

Descriptive Information Fields

Brief Title ^†

Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)

Official Title ^†

Incidence of Ocular Antibodies in Patients With Sturge - Weber Syndrome (SWS)

Brief Summary

Sturge-Weber Syndrome (SWS) is a neurological disorder characterized at birth by seizures and a large port-wine stain birthmark on the forehead and upper eyelid of one side of the face. SWS is also accompanied by an increased pressure within the eye (glaucoma) which can develop very early in life.

Glaucoma represents a group of ocular disorders that are characterized by the loss of retinal ganglion cells and their axons, damage to the optic nerve, and gradual loss of visual field. Recently, several studies provided evidence that there is a potential role of the immune system in the pathogenesis of glaucoma.

These findings suggest that there might be changes in systemic humoral immunity possibly underlying the optic neuropathy in at least some glaucoma patients.

Detailed Description

The ocular antibody profile in patients with SWS is unknown.The researchers want to study on blood and tear drop samples from patients with SWS to determine the incidence of ocular antibodies in patients with this syndrome.

Study Phase

Study Type ^†

Observational

Study Design ^†

Case-Only, Prospective

Primary Outcome Measure ^†

Secondary Outcome Measure ^†

Condition ^†

Sturge - Weber Syndrome (SWS)

Intervention ^†

MEDLINE PMIDs

Links

Recruitment Information Fields

Recruitment Status ^†

Completed

Enrollment ^†

Start Date ^†

July 2007

Completion Date

June 2008

Eligibility Criteria ^†

Inclusion Criteria:

Male and female volunteers with SWS of all ages

Exclusion Criteria:

Volunteers without SWS

Gender

Both

Ages

Accepts Healthy Volunteers

Contacts ^††

Location Countries ^†

United States

Administrative Information Fields

NCT ID ^†

NCT00610402

Organization ID

NIH-LAMMP P41-RR01192

Secondary IDs ^††

Study Sponsor ^†

University of California, Irvine

Collaborators ^††

Mainz University

Investigators ^†

Principal Investigator:

John S Nelson, M.D,PhD

Beckman Laser Institute Medical Clinic

Information Provided By

University of California, Irvine

Verification Date

July 2008

First Received Date ^†

January 25, 2008

Last Updated Date

July 25, 2008

^† Required WHO trial registration data element.
^†† WHO trial registration data element that is required only if it exists.