Albumin Use in Burn Patients

This study has been completed.
Sponsor:
Information provided by:
University of North Carolina, Chapel Hill
ClinicalTrials.gov Identifier:
NCT00609414
First received: January 24, 2008
Last updated: April 15, 2011
Last verified: April 2011

January 24, 2008
April 15, 2011
January 2005
October 2008   (final data collection date for primary outcome measure)
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Complete list of historical versions of study NCT00609414 on ClinicalTrials.gov Archive Site
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Albumin Use in Burn Patients
Albumin Use in Burn Patients

This is a study of why and how physicians use albumin during the first 72 hours after a burn injury.

While albumin has been a part of burn resuscitation for many years, its use remains varied and controversial. The purpose of this study is to describe the current practices of albumin administration during the first 72 hours after a burn injury. Participating sites will collect data on patients with at least a 20% Total Body Surface Area (TBSA) burn. Information will be recorded on type and extent of burn injury, basic demographic data, co-morbidities, outcomes and, for the first 72 hours post injury, if albumin was used and why, amount of resuscitation fluids and urine output, and use of vasopressors and diuretics.

Each participating site will retrospectively review 20 charts of consecutive admissions with at least a 20% TBSA burn. In addition, each site will collect data prospectively on 20 more patients with 20% TBSA burns. Prospective data is requested in order to capture as close as possible to "real time" the reasons physicians choose to give albumin. No Protected Health Information (PHI) will be recorded.

Data will be analyzed for patterns of albumin use and reasons for albumin administration.

Observational
Time Perspective: Prospective
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Non-Probability Sample

Patients who have 20% and greater Total Body Surface Area burns who received fluid resuscitation for these injuries.

Burns
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*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
460
October 2008
October 2008   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • Burn Injury, with and without inhalation injury

Exclusion Criteria:

  • <20% Total Body Surface Area Burned
  • Comfort care only for the burn injury
Both
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No
Contact information is only displayed when the study is recruiting subjects
United States,   Canada
 
NCT00609414
04-1392
No
Bruce A. Cairns MD, Department of Surgery, University of North Carolina at Chapel Hill
University of North Carolina, Chapel Hill
Not Provided
Principal Investigator: Bruce A. Cairns, MD North Carolina Jaycee Burn Center, University of North Carolina Hospitals
University of North Carolina, Chapel Hill
April 2011

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP