The Influence of Different Concentrations of Glucose in Culture Media on Fertilization and Embryo Quality - Tabular View

Tracking Information
First Received Date ^ICMJE	January 21, 2008
Last Updated Date	January 21, 2008
Start Date ^ICMJE	February 2008
Estimated Primary Completion Date	August 2009 (final data collection date for primary outcome measure)
Current Primary Outcome Measures ^ICMJE (submitted: January 21, 2008)	Fertilization rate and embryo quality [ Time Frame: 6 days ] [ Designated as safety issue: No ]
Original Primary Outcome Measures ^ICMJE	Same as current
Change History	No Changes Posted
Current Secondary Outcome Measures ^ICMJE
Original Secondary Outcome Measures ^ICMJE

Descriptive Information
Brief Title ^ICMJE	The Influence of Different Concentrations of Glucose in Culture Media on Fertilization and Embryo Quality
Official Title ^ICMJE	The Influence of Different Concentrations of Glucose in Culture Media(i.e: ISM1 vs. IVF) on Fertilization and Embryo Quality
Brief Summary	The aim of this study is to examine whether incubation of human oocytes until pronuclear stage, in different culture media containing high and low concentrations of glucose affect fertilization differently, not only in standard IVF cycles, but also after intracytoplasmatic sperm injection.In addition, we wish to determine whether exposure of oocytes to different concentrations of glucose until pronuclear stage has further effect on embryo quality and development until the blastocyst stage.
Detailed Description
Study Phase
Study Type ^ICMJE	Interventional
Study Design ^ICMJE	Treatment, Open Label, Parallel Assignment
Condition ^ICMJE	Fertility
Intervention ^ICMJE	Other: Universal IVF Medium + ISM1 Medium
Study Arms / Comparison Groups	Active Comparator: IVF Procedure-IVF Medium Active Comparator: IVF Procedure - ISM1 Medium Active Comparator: ICSI Procedure - IVF Medium Active Comparator: ICSI Procedure - ISM1 Medium
Publications *
* Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.

Recruitment Information
Recruitment Status ^ICMJE	Not yet recruiting
Estimated Enrollment ^ICMJE	100
Completion Date
Estimated Primary Completion Date	August 2009 (final data collection date for primary outcome measure)
Eligibility Criteria ^ICMJE	Inclusion Criteria: Patients undergoing IVF treatment in our clinic during study period Exclusion Criteria: Females older than 40 years Patients with less than 6 retrieved oocytes Male patients older than 50 years old Patients after testis biopsies
Gender	Both
Ages	18 Years to 50 Years
Accepts Healthy Volunteers	Yes
Contacts ^ICMJE
Location Countries ^ICMJE

Administrative Information
NCT ID ^ICMJE	NCT00606073
Responsible Party	Dr. Medeia Michaeli, Hillel Yaffe Medical Center
Study ID Numbers ^ICMJE	HYMC IRB#31/2007
Study Sponsor ^ICMJE	Hillel Yaffe Medical Center
Collaborators ^ICMJE
Investigators ^ICMJE
Information Provided By	Hillel Yaffe Medical Center
Verification Date	January 2008
^ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP