| January 16, 2008 |
| January 16, 2008 |
| January 2008 |
| January 2010 (final data collection date for primary outcome measure) |
| Functional tests, pain [ Time Frame: preoperatively, 6 weeks after operation (start of training), after 12 months training ] [ Designated as safety issue: Yes ] |
| Same as current |
| No Changes Posted |
| Quality of life,
Knee muscle strength and mobility,
Gait analysis
mobility of knee [ Time Frame: preoperatively, 6 weeks after operation (start of training), after 12 months training ] [ Designated as safety issue: Yes ] |
| Same as current |
| |
| Progressive Exercise After TKA |
| Progressive Exercise After Total Knee Arthroplasty: a Randomised Controlled Trial |
Total knee arthroplasty (TKA) is performed more than 7.000 times a year in Finland most often for osteoarthritis (OA). While pain is predictably reduced, function does not typically ever reach that of age-matched, uninjured subjects. Quadriceps weakness has been implicated in the development and progression of knee OA and is a significant problem after TKA. Advance to return to normal daily activities is not sufficient to restore knee function or quadriceps strength after TKA.
The aim of this study is to assess the effectiveness of progressive exercise program restoring knee strength, mobility and improving the functional outcome after primary TKA. |
Many studies have shown, that after TKA pain decreased significantly, but muscle strength of the operated knee did not recover and may stay under the preoperative level. To find out the effects of progressive exercise program we will perform 6 weeks after TKA a randomized clinical trial of lower extremity strength training using two subgroups of people: traditional exercise group and progressive exercise group. |
| |
| Interventional |
| Other, Randomized, Single Blind (Outcomes Assessor), Parallel Assignment, Efficacy Study |
| Osteoarthritis |
| Other: progressive exercise |
| Experimental: 1: progressive exercise |
| |
| |
| Recruiting |
| 120 |
| January 2011 |
| January 2010 (final data collection date for primary outcome measure) |
Inclusion Criteria:
- primary unilateral TKA for knee osteoarthritis
Exclusion Criteria:
- Rheumatoid arthritis, fibromyalgia, bilateral TKA, heart or lung disease, which prevent training, unstable serious disease (cancer), reduced co-operation (drug, alcohol abuse, mental illness)
|
| Both |
| 18 Years and older |
| No |
|
|
| Finland |
| |
| NCT00605124 |
| Jari Ylinen MD, PhD, Jyväskylä Central Hospital |
| KSSHP Dnro6/2007, KSSHP Dnro6/2007 |
| Jyväskylä Central Hospital |
|
| Study Director: |
Jari Ylinen, MD, PhD |
Central Finland Health Care District |
|
| Study Chair: |
Arja Häkkinen, PhD, Professor |
Central Finland Health Care District |
|
| Principal Investigator: |
Petri Salo, M.Sc. |
Central Finland Health Care District |
|
| Principal Investigator: |
Mirja Vuorenmaa, M.Sc. |
Central Finland Health Care District |
|
| Study Chair: |
Maija Pesola, MD |
Central Finland Health Care District |
|
|
| Jyväskylä Central Hospital |
| January 2008 |