Full Text View
Tabular View
No Study Results Posted
Related Studies
Low-Dose Chest Computed Tomography Screening for Lung Cancer in Survivors of Hodgkin's Disease
This study is currently recruiting participants.
Study NCT00601146   Information provided by Dana-Farber Cancer Institute
First Received: January 15, 2008   Last Updated: October 30, 2009   History of Changes

January 15, 2008
October 30, 2009
November 2006
April 2010   (final data collection date for primary outcome measure)
To prospectively collect data on chest CT screening for patients at increase lung-cancer risk after Hodgkin's disease. [ Time Frame: 3 years ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00601146 on ClinicalTrials.gov Archive Site
 
 
 
Low-Dose Chest Computed Tomography Screening for Lung Cancer in Survivors of Hodgkin's Disease
Low-Dose Chest Computed Tomography Screening for Lung Cancer in Survivors of Hodgkin's Disease

This research study is being done because patients with a history of chest radiation treatment for Hodgkin's disease have been shown to be at increased risk for developing lung cancer a number of years out from treatment. The risk appears to be further increased among patients with a smoking history. Currently, the practice is to recommend annual low-dose chest CT scans in survivors of Hodgkin's disease who have received prior chest radiation treatment and who have at least a moderate smoking history. In this study, the CT scans will be read and interpreted by the study radiologist, and the results recorded in a consistent manner.

- Participants will undergo a chest computed tomography (CT) scan once a year for a 3-year period.

 
Observational
Case-Only, Prospective
Lung Cancer
Procedure: chest computed tomography scan
 
 

*   Includes publications given by the data provider as well as publications identified by National Clinical Trials Identifier (NCT ID) in Medline.
 
Recruiting
200
 
April 2010   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • 5 years or longer from initial Hodgkin's disease diagnosis
  • Current age 18 or older
  • Received mediastinal irradiation and/or alkylating-agent based chemotherapy
  • Smoking history of 10-pack years or more, or current smoker
  • Pre-approval from the participant's insurance company for the CT study

Exclusion Criteria:

  • Patients with a history of lung cancer
  • Currently receiving treatment for another cancer diagnosis
  • Known diagnosis of any metastatic cancer
  • Pregnant women
Both
18 Years and older
No
Contact: Andrea K. Ng,, MD 617-732-7361
United States
 
NCT00601146
Andrea K. Ng, MD, Dana-Farber Cancer Institute/Brigham and Women's Hospital
06-122
Dana-Farber Cancer Institute
Brigham and Women's Hospital
Principal Investigator: Andrea K. Ng, MD Dana-Farber Cancer Institute/Brigham and Women's Hospital
Dana-Farber Cancer Institute
October 2009

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP