Family Based Contingency Management for Adolescent Alcohol Abuse

This study has been completed.
Sponsor:
Collaborator:
Information provided by (Responsible Party):
Dartmouth-Hitchcock Medical Center
ClinicalTrials.gov Identifier:
NCT00595478
First received: January 7, 2008
Last updated: August 18, 2014
Last verified: August 2014

January 7, 2008
August 18, 2014
August 2007
May 2014   (final data collection date for primary outcome measure)
Alcohol abstinence [ Time Frame: Weekly ] [ Designated as safety issue: No ]
Same as current
Complete list of historical versions of study NCT00595478 on ClinicalTrials.gov Archive Site
Days of alcohol use [ Time Frame: Monthly ] [ Designated as safety issue: No ]
Same as current
Not Provided
Not Provided
 
Family Based Contingency Management for Adolescent Alcohol Abuse
Family Based Contingency Management for Adolescent Alcohol Abuse

The goal is to adapt the family-based CM treatment to target primary adolescent alcohol abuse and dependence.

Specific Aim 1 is to provide a preliminary demonstration of the efficacy of a family-based CM intervention to treat adolescent alcohol abuse and dependence. CM components include:

  1. an incentive program to enhance the adolescent's engagement in the treatment process and engender alcohol abstinence by providing positive reinforcement for documented abstinence via breathalyzers administered by parents regularly at home, self and parent report, and clinic-based urine drug testing; and
  2. a parent management training program to enhance and maintain the positive effects of the incentive program by teaching parents how to effectively use contingency management in the home environment to motivate their adolescent to achieve abstinence and improve their behavior in other domains.

A randomized trial will determine whether the CM intervention enhances outcomes when added to a standard individual cognitive behavioral therapy (CBT).

Specific Aim 2 is to determine whether and how treatment interventions modify parental and adolescent risk and protective factors using observational and laboratory measures (parenting practices, family functioning, risk taking, delay discounting, and child and parent psychopathology) and to determine whether these factors are associated with outcomes over time.

Specific Aim 3 is to test gene x environment (treatment) interactions in adolescent substance abuse. Findings will extend the scientific evidence for CM and support the ability of parents to implement CM at home. Findings that support the CM model's efficacy will make a significant contribution to research on the treatment of adolescent alcohol abuse, which has lagged behind research on adult substance abuse and on adolescent illicit drug use.

Approximately 1.5 million youth ages 12-17 (representing 6.1% of all youth in that age range) are in need of treatment for alcohol abuse, yet only 7.2% of those in need of treatment received it. Importantly, most youth (90.5%) who were classified as needing treatment based on their self report of Adolescent Alcohol Study Plan; v.2; 3/30/12Page 2 of 35 symptoms, perceived no need for treatment. Thus, there is a need to develop treatments that target populations of alcohol abusing youth who are not highly motivated to change their substance use. New outpatient family based and contingency management interventions for adolescent marijuana abuse have been developed, yet none of these interventions has specifically targeted adolescent alcohol use. It is important to target primary alcohol abuse and dependence in adolescence as approximately 20% of treatment-seeking youth report primary problems with alcohol. The primary aim of this proposal is to adapt our family-based contingency-management treatment to target adolescent alcohol abuse and dependence. This project will develop, manualize, and pilot a contingency management intervention that includes two components. First, an incentive program will enhance the adolescent's engagement in the treatment process and engender alcohol abstinence by providing positive reinforcement for documented abstinence via breathalyzers administered by parents regularly at home, self and parent report, and clinic based urine drug testing. Second, a parent management training program will enhance and maintain the positive effects of the incentive program by teaching parents how to effectively use contingency management in the home environment to motivate their adolescent to achieve abstinence and improve their behavior in other domains.

Interventional
Not Provided
Allocation: Randomized
Endpoint Classification: Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Alcohol Abuse
  • Behavioral: Motivational Enhancement Therapy (MET)/CBT+CM
    Behavioral Treatment
  • Behavioral: Motivational Enhancement Therapy (MET)/CBT
    Behavioral Treatment
  • Experimental: 1
    Motivational Enhancement Therapy (MET)/CBT+CM/BPT
    Intervention: Behavioral: Motivational Enhancement Therapy (MET)/CBT+CM
  • Active Comparator: 2
    Motivational Enhancement Therapy (MET)/CBT
    Intervention: Behavioral: Motivational Enhancement Therapy (MET)/CBT
Not Provided

*   Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
 
Completed
120
May 2014
May 2014   (final data collection date for primary outcome measure)

Inclusion Criteria:

  • 12-18 years old (if 18, must attend high school and live at home)
  • Report using alcohol during the previous 30 days
  • Have a parent/guardian who can participate
  • Meet DSM criteria for either Alcohol Abuse or Dependence
  • Youth who meet DSM criteria for Alcohol Dependence may also meet criteria for Marijuana Abuse or Dependence and other Drug Abuse
  • Youth who meet DSM criteria for Alcohol Abuse, may also meet criteria for Marijuana or other Drug Abuse
  • Live within a 30-minute drive of the clinic

Exclusion Criteria:

  • Meet DSM criteria for Drug Dependence (other than Marijuana Dependence)
  • Meet DSM criteria for Alcohol Abuse with Marijuana Dependence. Use of other drugs will not be excluded
  • Participants will also be excluded if they exhibit an active psychosis
  • Have a severe medical or psychiatric illness that will limit participation
  • Are pregnant or breast-feeding
Both
12 Years to 18 Years
Yes
Contact information is only displayed when the study is recruiting subjects
United States
 
NCT00595478
85846, 1R01AA016917-01, 1R01AA016917-02, 1R01AA016917-03
Yes
Dartmouth-Hitchcock Medical Center
Dartmouth-Hitchcock Medical Center
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Principal Investigator: Catherine Stanger, Ph.D. Geisel School of Medicine at Dartmouth
Dartmouth-Hitchcock Medical Center
August 2014

ICMJE     Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP